C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: reticulon 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115310 RTN4 9606 - 2:54972187-55112621 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317610 RTN4-002 54972189-55050544 protein_coding
  ENST00000337526 RTN4-001 54972189-55050544 protein_coding
  ENST00000357376 RTN4-014 54972189-55049198 protein_coding
  ENST00000357732 RTN4-007 54972189-55050544 protein_coding
  ENST00000394609 RTN4-008 54972187-55010449 protein_coding
  ENST00000394611 RTN4-013 54972189-55050598 protein_coding
  ENST00000402434 RTN4-201 54972814-55050376 protein_coding
  ENST00000404909 RTN4-006 54972189-55050828 protein_coding
  ENST00000405240 RTN4-003 54972189-55046886 protein_coding
  ENST00000427710 RTN4-004 55027207-55112621 protein_coding
  ENST00000438462 RTN4-012 54973513-55049640 protein_coding
  ENST00000461004 RTN4-005 55056483-55112567 processed_transcript
  ENST00000485749 RTN4-011 54972797-54974191 processed_transcript
  ENST00000486085 RTN4-009 54972585-54987633 processed_transcript
  ENST00000491592 RTN4-010 54972796-54974019 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317610ENST00000337526ENST00000357732ENST00000394609ENST00000394611ENST00000402434ENST00000404909ENST00000405240ENST00000485749
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317610 257.737±0.00 62.547±0.00 12.119±0.00 79.526±0.00 194.398±184.33 80.839±69.97 13.809±11.94 130.329±0.00 6.499±0.10 113.095±106.45 N/A 64.278±40.21 74.458±17.77 40.057±7.58
ENST00000337526 N/A N/A N/A 24.834±0.00 N/A N/A 13.652±0.00 N/A N/A N/A 9.613±0.00 N/A N/A 8.016±0.53
ENST00000357732 N/A N/A N/A N/A N/A N/A N/A N/A 13.408±0.00 N/A N/A N/A N/A N/A
ENST00000394609 N/A N/A 14.387±0.00 113.421±40.58 8.950±0.00 16.891±0.00 1.884±0.00 54.345±35.44 15.492±0.85 10.028±0.00 41.112±27.75 15.615±9.17 35.865±0.00 N/A
ENST00000394611 N/A N/A N/A 19.803±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000402434 106.208±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.646±0.00 N/A N/A N/A
ENST00000404909 N/A N/A N/A 19.252±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.870±0.00
ENST00000405240 N/A N/A N/A 38.386±0.00 4.327±0.00 N/A N/A N/A 3.593±0.00 N/A N/A N/A N/A N/A
ENST00000485749 N/A N/A 19.434±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005515 IPI protein binding
GO:0005622 IMP intracellular
GO:0005635 IDA nuclear envelope
GO:0005783 IDA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006915 NAS apoptotic process
GO:0007399 IEA nervous system development
GO:0007413 ISS axonal fasciculation
GO:0016021 IEA integral component of membrane
GO:0021801 ISS cerebral cortex radial glia guided migration
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030308 IMP negative regulation of cell growth
GO:0030334 IDA regulation of cell migration
GO:0030517 IDA negative regulation of axon extension
GO:0042981 NAS regulation of apoptotic process
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0044822 IDA poly(A) RNA binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis
GO:0051960 IEA regulation of nervous system development
GO:0060317 IEA cardiac epithelial to mesenchymal transition
GO:0070062 IDA extracellular vesicular exosome
GO:0071786 IMP endoplasmic reticulum tubular network organization
GO:2000172 ISS regulation of branching morphogenesis of a nerve

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044601 rtn4a reticulon 4a protein_coding Danio_rerio
ENSMUSG00000020458 Rtn4 reticulon 4 protein_coding Mus_musculus

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