C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: reticulon 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020458 Rtn4 10090 + 11:29692947-29744331 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060992 Rtn4-009 29718563-29742916 protein_coding
  ENSMUST00000078830 Rtn4-007 29692947-29744331 protein_coding
  ENSMUST00000102841 Rtn4-008 29693774-29742916 protein_coding
  ENSMUST00000102842 Rtn4-006 29692947-29742916 protein_coding
  ENSMUST00000102843 Rtn4-005 29692947-29742916 protein_coding
  ENSMUST00000125735 Rtn4-002 29736400-29742347 processed_transcript
  ENSMUST00000126162 Rtn4-001 29740998-29742285 processed_transcript
  ENSMUST00000141719 Rtn4-003 29733773-29742347 processed_transcript
  ENSMUST00000156217 Rtn4-004 29733698-29742435 processed_transcript
  ENSMUST00000170731 Rtn4-201 29692948-29742111 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000060992ENSMUST00000078830ENSMUST00000102841ENSMUST00000102842ENSMUST00000102843ENSMUST00000156217ENSMUST00000170731
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000060992 46.212±13.35 N/A 23.013±0.00 172.163±0.00 58.304±23.87 N/A 6.732±1.15 20.994±6.14 33.280±8.08 N/A 403.880±39.98 48.121±20.39 N/A N/A
ENSMUST00000078830 N/A 40.194±22.42 N/A N/A 37.715±0.57 24.425±2.59 N/A 11.833±0.00 3.049±0.52 36.261±2.32 N/A 46.770±3.95 N/A N/A
ENSMUST00000102841 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.312±1.86 5.389±0.00 2.750±0.56
ENSMUST00000102842 24.315±7.90 N/A 93.243±19.52 51.217±14.77 17.001±1.64 11.761±3.39 4.155±1.39 10.713±4.08 18.378±6.90 28.465±7.52 N/A 24.443±13.91 59.111±19.03 4.258±0.00
ENSMUST00000102843 N/A N/A 13.130±1.86 60.549±11.12 N/A N/A 4.244±0.16 N/A 1.965±0.50 N/A N/A N/A 5.512±2.62 4.219±0.66
ENSMUST00000156217 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 72.777±0.00 107.865±0.00 17.670±0.00
ENSMUST00000170731 30.247±2.07 44.224±7.45 50.184±15.86 N/A 23.107±0.00 N/A 5.707±0.63 12.929±1.18 7.834±1.12 28.030±0.24 N/A N/A 17.179±2.74 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005635 ISS nuclear envelope
GO:0005783 IDA endoplasmic reticulum
GO:0007399 IDA nervous system development
GO:0007413 IMP axonal fasciculation
GO:0016021 IEA integral component of membrane
GO:0021801 IMP cerebral cortex radial glia guided migration
GO:0030176 ISS integral component of endoplasmic reticulum membrane
GO:0030308 IEA negative regulation of cell growth
GO:0030334 IEA regulation of cell migration
GO:0030517 ISS negative regulation of axon extension
GO:0042995 IDA cell projection
GO:0043025 IDA neuronal cell body
GO:0044822 IEA poly(A) RNA binding
GO:0051960 IMP regulation of nervous system development
GO:0060317 IMP cardiac epithelial to mesenchymal transition
GO:0070062 IEA extracellular vesicular exosome
GO:0071786 IEA endoplasmic reticulum tubular network organization
GO:2000172 IMP regulation of branching morphogenesis of a nerve

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044601 rtn4a reticulon 4a protein_coding Danio_rerio
ENSG00000115310 RTN4 reticulon 4 protein_coding Homo_sapiens

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