C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: melanophilin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115648 MLPH 9606 + 2:237485428-237555318 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264605 MLPH-001 237487168-237555318 protein_coding
  ENST00000338530 MLPH-004 237487251-237553994 protein_coding
  ENST00000409373 MLPH-005 237487276-237553994 protein_coding
  ENST00000410032 MLPH-002 237486410-237553996 protein_coding
  ENST00000415753 MLPH-019 237527435-237553724 protein_coding
  ENST00000422695 MLPH-009 237485428-237511050 protein_coding
  ENST00000429898 MLPH-010 237486409-237510674 protein_coding
  ENST00000432475 MLPH-020 237540449-237553722 nonsense_mediated_decay
  ENST00000434770 MLPH-022 237540865-237553991 protein_coding
  ENST00000436965 MLPH-018 237525728-237540959 protein_coding
  ENST00000437893 MLPH-008 237519935-237553956 protein_coding
  ENST00000464123 MLPH-007 237518029-237553991 retained_intron
  ENST00000468178 MLPH-003 237487251-237545769 processed_transcript
  ENST00000469619 MLPH-012 237487275-237511622 retained_intron
  ENST00000477222 MLPH-011 237487251-237510711 processed_transcript
  ENST00000477457 MLPH-021 237546405-237553843 retained_intron
  ENST00000477501 MLPH-013 237510070-237518572 processed_transcript
  ENST00000478712 MLPH-014 237518295-237552437 retained_intron
  ENST00000482528 MLPH-017 237525674-237527683 retained_intron
  ENST00000485956 MLPH-016 237519979-237537725 processed_transcript
  ENST00000489967 MLPH-023 237552027-237553811 retained_intron
  ENST00000494110 MLPH-015 237518414-237540446 retained_intron
  ENST00000495439 MLPH-006 237510087-237553993 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264605ENST00000338530ENST00000409373ENST00000410032ENST00000415753ENST00000434770ENST00000436965ENST00000437893ENST00000464123ENST00000468178ENST00000477222ENST00000477457ENST00000477501ENST00000478712ENST00000494110
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264605 N/A N/A N/A 0.038±0.00 1.301±0.00 0.347±0.00 0.203±0.00 N/A 0.148±0.00 N/A N/A N/A 0.277±0.00 N/A
ENST00000338530 0.986±0.00 1.341±0.00 0.065±0.00 N/A 3.521±1.75 1.344±0.27 3.791±3.28 1.084±0.25 4.152±3.69 6.680±4.25 3.954±0.00 4.902±1.85 2.075±1.00 1.151±0.00
ENST00000409373 N/A N/A N/A N/A N/A 0.982±0.00 N/A 0.867±0.00 N/A N/A N/A 4.263±0.21 0.576±0.00 N/A
ENST00000410032 1.079±0.00 N/A N/A N/A 4.059±0.00 N/A N/A N/A N/A N/A N/A N/A 0.206±0.00 N/A
ENST00000415753 N/A N/A N/A N/A N/A N/A 5.848±0.00 N/A N/A N/A 3.641±0.00 N/A N/A 1.622±0.00
ENST00000434770 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.082±0.00
ENST00000436965 N/A N/A N/A N/A N/A N/A N/A N/A 1.152±0.00 N/A N/A 3.686±0.00 N/A N/A
ENST00000437893 N/A N/A 0.056±0.00 0.065±0.00 N/A N/A N/A N/A N/A N/A N/A 4.529±0.00 N/A N/A
ENST00000464123 N/A N/A N/A N/A N/A 1.066±0.00 N/A N/A N/A N/A N/A N/A N/A 0.737±0.00
ENST00000468178 N/A N/A 0.025±0.00 N/A 1.662±0.00 N/A N/A N/A N/A 2.853±0.00 N/A 0.959±0.00 N/A 0.257±0.00
ENST00000477222 N/A N/A N/A 0.101±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000477457 N/A 2.622±0.00 N/A N/A N/A N/A N/A N/A 8.960±0.00 N/A N/A N/A 0.539±0.00 N/A
ENST00000477501 N/A N/A N/A N/A N/A N/A N/A N/A 1.662±0.00 N/A N/A N/A N/A N/A
ENST00000478712 0.810±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 2.361±0.00 N/A N/A N/A N/A
ENST00000494110 N/A N/A N/A 0.153±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.871±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L9 CIL_0008L9_0001 VISTA 2:237013177-237616630
CIL_0007RW CIL_0007RW_0001 VISTA 2:237313736-237917924
CIL_000439 CIL_000439_0001 CGP 2:237324003-237555318
CIL_0000XN CIL_0000XN_0001 CGP 2:237485428-237567175

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IEA stress fiber
GO:0003779 IEA actin binding
GO:0005515 IEA protein binding
GO:0005815 IEA microtubule organizing center
GO:0006605 IEA protein targeting
GO:0006886 IEA intracellular protein transport
GO:0015629 IEA actin cytoskeleton
GO:0017022 IEA myosin binding
GO:0017137 IEA Rab GTPase binding
GO:0030318 IEA melanocyte differentiation
GO:0030864 IEA cortical actin cytoskeleton
GO:0031489 IEA myosin V binding
GO:0032400 IEA melanosome localization
GO:0035371 IEA microtubule plus-end
GO:0043473 IEA pigmentation
GO:0046872 IEA metal ion binding
GO:0051010 IEA microtubule plus-end binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062481 mlphb melanophilin b protein_coding Danio_rerio
ENSDARG00000070991 mlpha melanophilin a protein_coding Danio_rerio
ENSMUSG00000026303 Mlph melanophilin protein_coding Mus_musculus

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