C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: melanophilin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026303 Mlph 10090 + 1:90915085-90951142 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027528 Mlph-001 90915085-90951142 protein_coding
  ENSMUST00000125149 Mlph-002 90927679-90928432 protein_coding
  ENSMUST00000136220 Mlph-003 90939169-90940239 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027528ENSMUST00000136220
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027528 0.812±0.54 0.423±0.09 2.362±0.33 0.080±0.05 8.336±2.53 16.920±2.76 0.194±0.08 1.665±0.18 0.051±0.05 4.880±0.30 0.093±0.02 2.448±1.17 1.065±0.79 0.235±0.18
ENSMUST00000136220 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.125±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L9 CIL_0008L9_0002 VISTA 1:90453497-91055787
CIL_0007RW CIL_0007RW_0002 VISTA 1:90676298-91284359
CIL_000439 CIL_000439_0002 CGP 1:90765923-90951142
CIL_0008D3 CIL_0008D3_0002 VISTA 1:90908179-91512308
CIL_0000XN CIL_0000XN_0002 CGP 1:90915085-90954027

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IDA stress fiber
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005815 IDA microtubule organizing center
GO:0006605 IMP protein targeting
GO:0015629 IDA actin cytoskeleton
GO:0017022 IDA myosin binding
GO:0017137 IDA Rab GTPase binding
GO:0030318 IMP melanocyte differentiation
GO:0030864 IDA cortical actin cytoskeleton
GO:0031489 IPI myosin V binding
GO:0032400 IMP melanosome localization
GO:0035371 IDA microtubule plus-end
GO:0042470 TAS melanosome
GO:0043473 IMP pigmentation
GO:0046872 IEA metal ion binding
GO:0051010 IPI microtubule plus-end binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062481 mlphb melanophilin b protein_coding Danio_rerio
ENSDARG00000070991 mlpha melanophilin a protein_coding Danio_rerio
ENSG00000115648 MLPH melanophilin protein_coding Homo_sapiens

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