C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAB3 GTPase activating protein subunit 1 (catalytic)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115839 RAB3GAP1 9606 + 2:135052265-135176394 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264158 RAB3GAP1-001 135052265-135170706 protein_coding
  ENST00000425393 RAB3GAP1-003 135052299-135059066 protein_coding
  ENST00000442034 RAB3GAP1-002 135052298-135169989 protein_coding
  ENST00000487003 RAB3GAP1-004 135089654-135176394 processed_transcript
  ENST00000489858 RAB3GAP1-006 135124080-135130705 retained_intron
  ENST00000497080 RAB3GAP1-007 135168548-135169977 retained_intron
  ENST00000539493 RAB3GAP1-201 135089855-135175590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264158ENST00000442034ENST00000539493
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264158 2.312±0.00 N/A 1.848±0.00 3.501±0.00 2.918±0.67 4.941±0.00 3.051±0.00 0.774±0.00 2.397±0.81 3.930±1.79 4.290±0.00 5.287±2.19 6.199±0.94 3.305±0.00
ENST00000442034 7.551±0.00 5.685±0.00 1.454±0.00 10.874±0.36 4.777±2.73 5.856±0.93 4.597±2.42 4.410±3.55 3.521±1.19 5.740±0.28 4.062±0.70 4.775±0.02 4.021±0.00 6.572±1.78
ENST00000539493 N/A N/A 3.451±0.00 6.181±0.00 N/A N/A N/A 2.344±0.00 N/A N/A 2.844±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VQ CIL_0006VQ_0001 CGP 2:134964491-135176394
CIL_0006VP CIL_0006VP_0001 CGP 2:135052265-135531236

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005097 IDA Rab GTPase activator activity
GO:0005737 IDA cytoplasm
GO:0007420 IMP brain development
GO:0017112 IMP Rab guanyl-nucleotide exchange factor activity
GO:0017137 IPI Rab GTPase binding
GO:0021854 IMP hypothalamus development
GO:0032851 ISS positive regulation of Rab GTPase activity
GO:0033126 IMP positive regulation of GTP catabolic process
GO:0034389 IMP lipid particle organization
GO:0043010 IMP camera-type eye development
GO:0043087 IDA regulation of GTPase activity
GO:0043234 IDA protein complex
GO:0048172 ISS regulation of short-term neuronal synaptic plasticity
GO:0060079 ISS regulation of excitatory postsynaptic membrane potential
GO:0060325 IMP face morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071782 IDA endoplasmic reticulum tubular network
GO:0097051 IMP establishment of protein localization to endoplasmic reticulum membrane
GO:1903233 ISS regulation of calcium ion-dependent exocytosis of neurotransmitter
GO:1903373 IMP positive regulation of endoplasmic reticulum tubular network organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086726 rab3gap1 RAB3 GTPase activating protein subunit 1 protein_coding Danio_rerio
ENSMUSG00000036104 Rab3gap1 RAB3 GTPase activating protein subunit 1 protein_coding Mus_musculus

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