C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAB3 GTPase activating protein subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036104 Rab3gap1 10090 + 1:127868773-127943868 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037649 Rab3gap1-001 127868773-127943868 protein_coding
  ENSMUST00000131884 Rab3gap1-004 127938205-127942911 processed_transcript
  ENSMUST00000142662 Rab3gap1-003 127868802-127904033 retained_intron
  ENSMUST00000150945 Rab3gap1-002 127900913-127905934 retained_intron
  ENSMUST00000186865 Rab3gap1-006 127868789-127882448 processed_transcript
  ENSMUST00000189259 Rab3gap1-005 127923073-127926267 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037649ENSMUST00000131884ENSMUST00000186865
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037649 8.162±1.63 7.673±0.65 8.496±0.34 10.956±5.67 7.561±1.62 8.170±1.91 4.822±0.75 8.421±1.11 4.679±0.76 9.141±0.53 7.328±0.40 7.595±3.53 9.081±1.36 4.153±0.36
ENSMUST00000131884 N/A 9.607±0.69 N/A 71.619±0.00 N/A N/A N/A N/A N/A N/A N/A 17.562±11.07 N/A 8.850±0.00
ENSMUST00000186865 10.191±0.17 3.855±0.23 26.105±3.58 40.702±2.22 11.899±3.27 20.541±4.64 7.869±1.28 10.358±0.87 12.557±3.79 11.611±0.80 7.428±0.86 11.293±4.49 68.030±35.90 13.024±1.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VQ CIL_0006VQ_0002 CGP 1:127815253-127943868
CIL_0006VP CIL_0006VP_0002 CGP 1:127868773-128103047

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005097 ISO Rab GTPase activator activity
GO:0005737 ISS cytoplasm
GO:0007420 IEA brain development
GO:0010807 TAS regulation of synaptic vesicle priming
GO:0017112 IEA Rab guanyl-nucleotide exchange factor activity
GO:0017137 ISS Rab GTPase binding
GO:0021854 IEA hypothalamus development
GO:0032851 ISS positive regulation of Rab GTPase activity
GO:0033126 ISS positive regulation of GTP catabolic process
GO:0034389 ISO lipid particle organization
GO:0043010 IEA camera-type eye development
GO:0043087 IEA regulation of GTPase activity
GO:0043234 ISS protein complex
GO:0048172 IMP regulation of short-term neuronal synaptic plasticity
GO:0048489 NAS synaptic vesicle transport
GO:0050821 IC protein stabilization
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060325 IEA face morphogenesis
GO:0070062 IEA extracellular vesicular exosome
GO:0071782 ISS endoplasmic reticulum tubular network
GO:0097051 ISS establishment of protein localization to endoplasmic reticulum membrane
GO:1903233 IMP regulation of calcium ion-dependent exocytosis of neurotransmitter
GO:1903373 ISS positive regulation of endoplasmic reticulum tubular network organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086726 rab3gap1 RAB3 GTPase activating protein subunit 1 protein_coding Danio_rerio
ENSG00000115839 RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) protein_coding Homo_sapiens

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