C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: origin recognition complex, subunit 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115942 ORC2 9606 - 2:200908973-200963680 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000234296 ORC2-001 200908973-200963680 protein_coding
  ENST00000410039 ORC2-006 200949554-200963377 protein_coding
  ENST00000457595 ORC2-007 200957422-200963258 protein_coding
  ENST00000464147 ORC2-002 200910454-200926904 retained_intron
  ENST00000467605 ORC2-005 200942684-200963680 processed_transcript
  ENST00000474877 ORC2-004 200933876-200943159 processed_transcript
  ENST00000487853 ORC2-003 200920221-200921738 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000234296ENST00000464147
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000234296 3.784±0.00 3.373±0.00 1.730±0.00 3.342±0.12 2.720±0.56 2.233±0.71 2.303±0.88 2.850±0.69 1.731±0.95 2.655±0.88 1.379±0.46 7.603±4.15 2.600±1.06 10.147±3.48
ENST00000464147 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.878±5.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002AW CIL_0002AW_0001 CGP 2:200889327-200963680
CIL_0002AT CIL_0002AT_0001 CGP 2:200908973-201071671

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000785 IEA chromatin
GO:0000792 IEA heterochromatin
GO:0000808 IDA:IEA origin recognition complex
GO:0000939 IEA condensed chromosome inner kinetochore
GO:0003688 IEA DNA replication origin binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005664 IDA nuclear origin of replication recognition complex
GO:0005886 IDA plasma membrane
GO:0006260 IEA:TAS DNA replication
GO:0006270 TAS DNA replication initiation
GO:0016020 IDA membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090203 ORC2 origin recognition complex, subunit 2 protein_coding Danio_rerio
ENSMUSG00000026037 Orc2 origin recognition complex, subunit 2 protein_coding Mus_musculus

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