C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: splicing factor proline/glutamine-rich
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116560 SFPQ 9606 - 1:35176378-35193148 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357214 SFPQ-001 35182932-35193148 protein_coding
  ENST00000460428 SFPQ-003 35176378-35188042 nonsense_mediated_decay
  ENST00000466213 SFPQ-005 35176380-35179246 processed_transcript
  ENST00000466745 SFPQ-008 35176380-35179105 processed_transcript
  ENST00000468598 SFPQ-004 35176378-35180645 processed_transcript
  ENST00000470472 SFPQ-002 35176378-35190574 nonsense_mediated_decay
  ENST00000471991 SFPQ-009 35176378-35177661 processed_transcript
  ENST00000485365 SFPQ-007 35176380-35181606 processed_transcript
  ENST00000485454 SFPQ-006 35177209-35178136 processed_transcript
  ENST00000490668 SFPQ-010 35176380-35181344 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357214ENST00000466213ENST00000468598ENST00000470472
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357214 24.306±0.00 24.083±0.00 8.999±0.00 12.275±4.73 12.552±6.98 16.703±0.00 10.744±5.94 18.338±14.47 9.196±0.00 7.830±3.34 23.394±0.00 42.986±26.44 45.052±26.74 60.392±8.11
ENST00000466213 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.950±0.00 N/A N/A
ENST00000468598 4.457±0.00 N/A N/A 6.159±0.79 N/A N/A 3.533±0.00 9.429±0.00 1.964±0.00 5.558±1.89 2.380±0.00 15.047±1.03 N/A N/A
ENST00000470472 29.202±0.00 75.532±0.00 N/A 27.530±0.00 36.140±0.00 39.556±0.00 10.840±0.00 50.999±0.00 9.468±0.00 30.818±0.00 31.590±0.00 81.853±19.13 48.844±26.75 90.509±7.96

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000166 IEA nucleotide binding
GO:0000380 IMP alternative mRNA splicing, via spliceosome
GO:0000785 IDA chromatin
GO:0000976 ISS transcription regulatory region sequence-specific DNA binding
GO:0001047 ISS core promoter binding
GO:0003676 IEA nucleic acid binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006351 IEA transcription, DNA-templated
GO:0006397 TAS mRNA processing
GO:0008380 TAS RNA splicing
GO:0016363 IDA nuclear matrix
GO:0042382 IDA paraspeckles
GO:0042752 ISS regulation of circadian rhythm
GO:0042754 ISS negative regulation of circadian rhythm
GO:0042826 IPI histone deacetylase binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0048511 IEA rhythmic process
GO:0070932 ISS histone H3 deacetylation
GO:1902177 IDA positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011564 sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) protein_coding Danio_rerio
ENSMUSG00000028820 Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) protein_coding Mus_musculus

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