C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin T type 2 (cardiac)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118194 TNNT2 9606 - 1:201359008-201377762 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000236918 TNNT2-201 201359009-201373254 protein_coding
  ENST00000360372 TNNT2-202 201359009-201373254 protein_coding
  ENST00000367315 TNNT2-203 201359015-201373266 protein_coding
  ENST00000367317 TNNT2-204 201359009-201373254 protein_coding
  ENST00000367318 TNNT2-005 201359008-201377661 protein_coding
  ENST00000367320 TNNT2-003 201359024-201377661 protein_coding
  ENST00000367322 TNNT2-001 201359008-201377680 protein_coding
  ENST00000412633 TNNT2-012 201365276-201377664 protein_coding
  ENST00000421663 TNNT2-205 201359019-201377664 protein_coding
  ENST00000422165 TNNT2-014 201365245-201377652 protein_coding
  ENST00000438742 TNNT2-002 201359245-201377664 protein_coding
  ENST00000445079 TNNT2-021 201366395-201368314 retained_intron
  ENST00000455702 TNNT2-010 201363356-201377633 protein_coding
  ENST00000458432 TNNT2-206 201359009-201377700 protein_coding
  ENST00000460780 TNNT2-011 201359008-201364188 processed_transcript
  ENST00000466570 TNNT2-006 201363329-201373315 processed_transcript
  ENST00000472177 TNNT2-020 201367453-201377680 retained_intron
  ENST00000475686 TNNT2-015 201366843-201373265 processed_transcript
  ENST00000476888 TNNT2-018 201359008-201363350 processed_transcript
  ENST00000477035 TNNT2-017 201361012-201361357 processed_transcript
  ENST00000491504 TNNT2-004 201359008-201377680 retained_intron
  ENST00000494095 TNNT2-007 201367143-201375368 retained_intron
  ENST00000503459 TNNT2-022 201363927-201367808 retained_intron
  ENST00000509001 TNNT2-008 201359034-201377762 protein_coding
  ENST00000515042 TNNT2-019 201360827-201366966 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainHeartKidneyLiverLungMusclePlacentaTestisENST00000236918ENST00000360372ENST00000367317ENST00000367318ENST00000367322ENST00000421663ENST00000455702ENST00000458432ENST00000491504ENST00000494095ENST00000503459ENST00000515042
Transcript ID Adipose Adrenal Bladder Brain Heart Kidney Liver Lung Muscle Placenta Testis
ENST00000236918 N/A N/A N/A 9.229±0.00 N/A N/A N/A N/A 0.910±0.00 N/A N/A
ENST00000360372 N/A N/A 0.890±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000367317 N/A N/A N/A 1.593±1.35 455.528±385.41 N/A N/A N/A 1.661±0.00 N/A N/A
ENST00000367318 N/A N/A N/A N/A 1510.086±1337.75 N/A N/A N/A N/A 28.554±0.00 1.011±0.00
ENST00000367322 N/A N/A N/A N/A N/A 26.246±0.00 3.466±0.00 N/A N/A 7.403±1.95 1.162±0.00
ENST00000421663 N/A N/A N/A N/A N/A N/A N/A 10.921±0.00 N/A N/A 0.073±0.00
ENST00000455702 0.473±0.00 N/A N/A N/A N/A N/A N/A N/A 1.273±0.00 N/A N/A
ENST00000458432 N/A N/A N/A N/A N/A N/A 0.942±0.00 N/A N/A N/A 0.062±0.00
ENST00000491504 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.065±0.00
ENST00000494095 N/A 0.112±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000503459 0.441±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000515042 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.444±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IDA actin binding
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005523 IDA tropomyosin binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005861 IEA:IDA troponin complex
GO:0005865 IDA striated muscle thin filament
GO:0006200 IDA ATP catabolic process
GO:0006936 IEA muscle contraction
GO:0006937 IEA regulation of muscle contraction
GO:0007507 IEA heart development
GO:0008016 IMP regulation of heart contraction
GO:0016887 IDA ATPase activity
GO:0030016 IEA myofibril
GO:0030017 TAS sarcomere
GO:0030049 IDA muscle filament sliding
GO:0030172 IPI troponin C binding
GO:0031013 IPI troponin I binding
GO:0032780 IDA negative regulation of ATPase activity
GO:0032781 IDA positive regulation of ATPase activity
GO:0045214 IEA sarcomere organization
GO:0051592 IDA response to calcium ion
GO:0055009 IEA atrial cardiac muscle tissue morphogenesis
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032242 tnnt2c troponin T2c, cardiac protein_coding Danio_rerio
ENSMUSG00000026414 Tnnt2 troponin T2, cardiac protein_coding Mus_musculus

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