C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin T2, cardiac
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026414 Tnnt2 10090 + 1:135836354-135852260 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027671 Tnnt2-201 135840875-135852260 protein_coding
  ENSMUST00000112085 Tnnt2-202 135840875-135852260 protein_coding
  ENSMUST00000112086 Tnnt2-203 135840875-135852260 protein_coding
  ENSMUST00000112087 Tnnt2-001 135840857-135852260 protein_coding
  ENSMUST00000178204 Tnnt2-204 135836386-135852260 protein_coding
  ENSMUST00000178854 Tnnt2-205 135840875-135852260 protein_coding
  ENSMUST00000179863 Tnnt2-206 135840875-135852260 protein_coding
  ENSMUST00000186225 Tnnt2-006 135836390-135844752 retained_intron
  ENSMUST00000188028 Tnnt2-004 135836354-135852260 protein_coding
  ENSMUST00000188098 Tnnt2-007 135849450-135849741 retained_intron
  ENSMUST00000189355 Tnnt2-002 135836413-135852260 protein_coding
  ENSMUST00000189732 Tnnt2-003 135836410-135852260 protein_coding
  ENSMUST00000189826 Tnnt2-008 135840699-135849459 protein_coding
  ENSMUST00000190451 Tnnt2-009 135836402-135848049 protein_coding
  ENSMUST00000191055 Tnnt2-005 135836390-135839719 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027671ENSMUST00000112085ENSMUST00000112087ENSMUST00000178204ENSMUST00000178854ENSMUST00000179863ENSMUST00000186225ENSMUST00000188028ENSMUST00000188098ENSMUST00000189355ENSMUST00000189732ENSMUST00000189826ENSMUST00000190451ENSMUST00000191055
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027671 N/A 1.148±0.46 N/A N/A N/A 0.733±0.26 684.301±56.93 0.273±0.07 0.053±0.03 12.427±4.43 0.491±0.00 1.436±0.80 N/A 0.223±0.00
ENSMUST00000112085 N/A N/A N/A N/A 0.278±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000112087 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.279±0.29 N/A N/A
ENSMUST00000178204 1.217±0.00 N/A N/A N/A N/A N/A N/A 0.232±0.08 N/A 12.375±0.74 N/A 0.771±0.35 N/A 1.572±0.00
ENSMUST00000178854 N/A N/A N/A N/A 0.641±0.00 N/A N/A N/A 0.008±0.00 N/A 0.985±0.30 N/A N/A N/A
ENSMUST00000179863 0.920±0.84 0.519±0.26 72.729±9.09 0.074±0.00 N/A 0.889±0.08 N/A N/A 0.842±0.89 N/A 0.759±0.31 2.544±0.77 2.852±1.26 N/A
ENSMUST00000186225 0.115±0.09 0.160±0.03 N/A 0.023±0.00 0.073±0.03 0.112±0.02 N/A 0.026±0.01 0.023±0.01 N/A N/A 0.339±0.09 0.341±0.00 0.097±0.01
ENSMUST00000188028 N/A N/A N/A 1.102±0.00 N/A N/A N/A N/A 0.773±0.47 N/A N/A N/A N/A N/A
ENSMUST00000188098 N/A N/A N/A N/A N/A 1.895±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000189355 N/A N/A N/A N/A N/A N/A 1279.068±272.80 0.434±0.00 N/A 13.214±3.41 0.423±0.16 N/A N/A N/A
ENSMUST00000189732 N/A N/A N/A N/A N/A N/A N/A 0.113±0.00 0.086±0.04 N/A N/A N/A N/A N/A
ENSMUST00000189826 N/A N/A N/A 3.141±3.05 N/A N/A N/A 0.160±0.00 0.068±0.00 N/A N/A 4.827±0.00 4.413±0.87 N/A
ENSMUST00000190451 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.801±0.00 N/A N/A
ENSMUST00000191055 0.150±0.14 0.079±0.02 N/A N/A 0.258±0.18 0.322±0.07 N/A 0.048±0.01 0.015±0.00 N/A N/A 0.287±0.07 0.346±0.06 0.061±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005200 IDA structural constituent of cytoskeleton
GO:0005523 ISS tropomyosin binding
GO:0005737 IDA cytoplasm
GO:0005861 IDA troponin complex
GO:0005865 ISS striated muscle thin filament
GO:0006200 IEA ATP catabolic process
GO:0006936 IDA muscle contraction
GO:0006937 IEA regulation of muscle contraction
GO:0007507 IMP heart development
GO:0008016 IMP regulation of heart contraction
GO:0016887 IEA ATPase activity
GO:0030016 IDA myofibril
GO:0030017 IDA sarcomere
GO:0030049 ISS muscle filament sliding
GO:0030172 ISS troponin C binding
GO:0031013 ISS troponin I binding
GO:0032780 ISS negative regulation of ATPase activity
GO:0032781 ISS positive regulation of ATPase activity
GO:0045214 IMP sarcomere organization
GO:0051592 ISS response to calcium ion
GO:0055009 IMP atrial cardiac muscle tissue morphogenesis
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032242 tnnt2c troponin T2c, cardiac protein_coding Danio_rerio
ENSG00000118194 TNNT2 troponin T type 2 (cardiac) protein_coding Homo_sapiens

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