C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118777 ABCG2 9606 - 4:88090264-88231322 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237612 ABCG2-001 88090269-88158912 protein_coding
  ENST00000503830 ABCG2-004 88131844-88159239 protein_coding
  ENST00000505480 ABCG2-003 88131844-88158671 protein_coding
  ENST00000515655 ABCG2-002 88090264-88231322 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000237612ENST00000503830ENST00000515655
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000237612 0.857±0.00 1.008±0.00 2.825±2.08 0.459±0.22 2.762±2.16 N/A 4.223±3.15 1.135±0.00 0.909±0.08 N/A 0.900±0.23 2.229±0.48 0.396±0.02
ENST00000503830 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.151±0.00 N/A N/A N/A
ENST00000515655 N/A N/A 1.287±0.00 N/A N/A 0.278±0.00 N/A N/A N/A N/A 0.602±0.49 N/A 0.185±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RO CIL_0001RO_0002 CGP 4:88007668-88231322
CIL_0001RP CIL_0001RP_0002 CGP 4:88090264-88284769

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 TAS transporter activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005886 TAS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 TAS transport
GO:0006855 TAS drug transmembrane transport
GO:0006879 TAS cellular iron ion homeostasis
GO:0015232 TAS heme transporter activity
GO:0015886 TAS heme transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0042493 TAS response to drug
GO:0042626 TAS ATPase activity, coupled to transmembrane movement of substances
GO:0042803 IDA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046415 IMP urate metabolic process
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016818 abcg2d ATP-binding cassette, sub-family G (WHITE), member 2d protein_coding Danio_rerio
ENSDARG00000043037 abcg2a ATP-binding cassette, sub-family G (WHITE), member 2a protein_coding Danio_rerio
ENSMUSG00000029299 Abcg3 ATP-binding cassette, sub-family G (WHITE), member 3 protein_coding Mus_musculus
ENSMUSG00000029802 Abcg2 ATP-binding cassette, sub-family G (WHITE), member 2 protein_coding Mus_musculus

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