C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cleavage and polyadenylation specific factor 3, 73kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119203 CPSF3 9606 + 2:9423568-9473101 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000238112 CPSF3-001 9423568-9473101 protein_coding
  ENST00000460593 CPSF3-002 9423884-9473092 protein_coding
  ENST00000475482 CPSF3-003 9423651-9432688 protein_coding
  ENST00000489403 CPSF3-005 9456977-9473098 processed_transcript
  ENST00000489629 CPSF3-004 9441730-9448350 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000238112ENST00000460593ENST00000475482ENST00000489403ENST00000489629
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000238112 8.610±0.00 9.140±0.00 1.779±0.00 4.483±1.00 6.710±3.62 4.453±0.82 2.665±2.32 6.650±3.74 4.334±0.15 2.286±0.30 3.610±2.61 6.571±2.10 9.355±2.67 23.851±6.16
ENST00000460593 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.093±0.00
ENST00000475482 N/A N/A 1.032±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000489403 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 43.093±0.00 41.854±0.00 122.870±0.00
ENST00000489629 N/A N/A N/A N/A 3.561±0.00 N/A N/A N/A N/A N/A 5.115±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057K CIL_00057K_0001 CGP 2:9403475-9473101
CIL_00057M CIL_00057M_0001 CGP 2:9423568-9496543

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003723 ISS RNA binding
GO:0004521 ISS endoribonuclease activity
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005847 IDA mRNA cleavage and polyadenylation specificity factor complex
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006378 TAS mRNA polyadenylation
GO:0006379 TAS mRNA cleavage
GO:0006398 IDA histone mRNA 3'-end processing
GO:0006406 TAS mRNA export from nucleus
GO:0008380 TAS RNA splicing
GO:0008409 ISS 5'-3' exonuclease activity
GO:0010467 TAS gene expression
GO:0030529 IEA ribonucleoprotein complex
GO:0031124 TAS mRNA 3'-end processing
GO:0046872 IEA metal ion binding
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027649 cpsf3 cleavage and polyadenylation specific factor 3 protein_coding Danio_rerio
ENSMUSG00000054309 Cpsf3 cleavage and polyadenylation specificity factor 3 protein_coding Mus_musculus

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