C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2A activator, regulatory subunit 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119383 PPP2R4 9606 + 9:129110950-129148946 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337738 PPP2R4-201 129111314-129148945 protein_coding
  ENST00000347048 PPP2R4-015 129111409-129148946 protein_coding
  ENST00000348141 PPP2R4-020 129111336-129148946 protein_coding
  ENST00000355007 PPP2R4-016 129111414-129148946 protein_coding
  ENST00000357197 PPP2R4-202 129111314-129148945 protein_coding
  ENST00000358994 PPP2R4-010 129110950-129148944 protein_coding
  ENST00000393370 PPP2R4-011 129111318-129148946 protein_coding
  ENST00000411917 PPP2R4-001 129136497-129142982 protein_coding
  ENST00000414331 PPP2R4-009 129111435-129134842 protein_coding
  ENST00000414510 PPP2R4-003 129140008-129148287 protein_coding
  ENST00000417504 PPP2R4-021 129119022-129131639 protein_coding
  ENST00000417728 PPP2R4-017 129111688-129142552 protein_coding
  ENST00000419582 PPP2R4-005 129141646-129147957 protein_coding
  ENST00000423100 PPP2R4-002 129139382-129147998 protein_coding
  ENST00000432124 PPP2R4-024 129140100-129143087 protein_coding
  ENST00000432651 PPP2R4-006 129141954-129148006 protein_coding
  ENST00000434095 PPP2R4-007 129142025-129147995 protein_coding
  ENST00000435132 PPP2R4-014 129141994-129147772 protein_coding
  ENST00000435305 PPP2R4-004 129140118-129142940 protein_coding
  ENST00000436883 PPP2R4-023 129140008-129143654 protein_coding
  ENST00000440346 PPP2R4-019 129119513-129129065 protein_coding
  ENST00000445241 PPP2R4-013 129111413-129136566 protein_coding
  ENST00000452489 PPP2R4-203 129111688-129148945 protein_coding
  ENST00000453358 PPP2R4-018 129111868-129134827 protein_coding
  ENST00000455240 PPP2R4-022 129136471-129138111 protein_coding
  ENST00000455292 PPP2R4-012 129110964-129136556 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000337738ENST00000347048ENST00000355007ENST00000357197ENST00000358994ENST00000393370ENST00000414331ENST00000414510ENST00000423100ENST00000452489ENST00000455292
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000337738 N/A 11.195±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.871±0.00 4.727±0.00 17.811±0.00
ENST00000347048 N/A N/A N/A N/A N/A N/A N/A 21.529±0.00 20.172±0.00 N/A N/A 22.728±3.32 N/A
ENST00000355007 14.222±0.00 21.660±0.00 1.586±0.00 14.800±0.00 18.185±0.00 N/A N/A N/A N/A N/A 3.400±0.00 N/A 46.659±0.00
ENST00000357197 N/A N/A N/A 4.099±0.00 N/A N/A N/A N/A N/A 0.954±0.00 N/A N/A N/A
ENST00000358994 N/A N/A N/A N/A 1.710±0.00 N/A N/A 3.266±0.00 N/A 1.917±0.00 N/A N/A N/A
ENST00000393370 10.210±0.00 N/A N/A 28.070±18.52 13.113±0.00 9.516±6.90 14.590±0.00 30.863±0.00 1.418±0.00 11.996±0.00 25.237±10.84 17.126±1.98 41.455±2.97
ENST00000414331 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.492±0.00 N/A N/A
ENST00000414510 N/A N/A N/A N/A N/A N/A 5.348±0.00 N/A N/A N/A N/A N/A N/A
ENST00000423100 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.186±0.00 N/A N/A N/A
ENST00000452489 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.654±0.00 N/A
ENST00000455292 N/A N/A N/A N/A 1.728±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZA CIL_0005ZA_0001 CGP 9:129081100-129111189
CIL_0003C7 CIL_0003C7_0001 CGP 9:129094810-129148946
CIL_0003CA CIL_0003CA_0001 CGP 9:129110950-129178262

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 TAS protein phosphatase type 2A complex
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0005102 IPI receptor binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006200 IDA ATP catabolic process
GO:0006457 IEA protein folding
GO:0008160 IDA protein tyrosine phosphatase activator activity
GO:0008601 TAS protein phosphatase type 2A regulator activity
GO:0016887 IDA ATPase activity
GO:0019211 IEA phosphatase activator activity
GO:0030472 IBA mitotic spindle organization in nucleus
GO:0032515 IDA negative regulation of phosphoprotein phosphatase activity
GO:0032516 IDA positive regulation of phosphoprotein phosphatase activity
GO:0034704 IDA calcium channel complex
GO:0035307 IDA positive regulation of protein dephosphorylation
GO:0035308 IDA negative regulation of protein dephosphorylation
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043085 IEA positive regulation of catalytic activity
GO:0043666 IDA regulation of phosphoprotein phosphatase activity
GO:0046982 TAS protein heterodimerization activity
GO:0051721 IDA protein phosphatase 2A binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031985 ppp2r4 protein phosphatase 2A activator, regulatory subunit 4 protein_coding Danio_rerio
ENSMUSG00000039515 Ppp2r4 protein phosphatase 2A activator, regulatory subunit B protein_coding Mus_musculus

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