C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase 2A activator, regulatory subunit 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000393370 PPP2R4-011 ENSG00000119383 9606 + 9:129111318-129148946 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000393370
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000393370 10.210±0.00 28.070±18.52 13.113±0.00 9.516±6.90 14.590±0.00 30.863±0.00 1.418±0.00 11.996±0.00 25.237±10.84 17.126±1.98 41.455±2.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZA CIL_0005ZA_0001 CGP 9:129081100-129111189
CIL_0003C7 CIL_0003C7_0001 CGP 9:129094810-129148946
CIL_0003CA CIL_0003CA_0001 CGP 9:129110950-129178262

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000159 TAS protein phosphatase type 2A complex
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0005102 IPI receptor binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006200 IDA ATP catabolic process
GO:0006457 IEA protein folding
GO:0008160 IDA protein tyrosine phosphatase activator activity
GO:0008601 TAS protein phosphatase type 2A regulator activity
GO:0016887 IDA ATPase activity
GO:0019211 IEA phosphatase activator activity
GO:0030472 IBA mitotic spindle organization in nucleus
GO:0032515 IDA negative regulation of phosphoprotein phosphatase activity
GO:0032516 IDA positive regulation of phosphoprotein phosphatase activity
GO:0034704 IDA calcium channel complex
GO:0035307 IDA positive regulation of protein dephosphorylation
GO:0035308 IDA negative regulation of protein dephosphorylation
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043085 IEA positive regulation of catalytic activity
GO:0043666 IDA regulation of phosphoprotein phosphatase activity
GO:0046982 TAS protein heterodimerization activity
GO:0051721 IDA protein phosphatase 2A binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000042055 Ppp2r4-001 protein_coding Mus_musculus 0 1376
ENSMUST00000125743 Ppp2r4-004 retained_intron Mus_musculus 0 898
ENSMUST00000113603 Ppp2r4-002 protein_coding Mus_musculus 0 848
ENSMUST00000128516 Ppp2r4-005 retained_intron Mus_musculus 0 481
ENSMUST00000137741 Ppp2r4-008 processed_transcript Mus_musculus 0 302
ENSMUST00000136009 Ppp2r4-007 protein_coding Mus_musculus 0 302
ENSMUST00000152165 Ppp2r4-013 nonsense_mediated_decay Mus_musculus 0 302
ENSMUST00000113601 Ppp2r4-003 protein_coding Mus_musculus 0 302
ENSMUST00000131476 Ppp2r4-006 protein_coding Mus_musculus 0 298
ENSMUST00000135105 Ppp2r4-011 processed_transcript Mus_musculus 2e-38 165
ENSMUST00000125561 Ppp2r4-009 nonsense_mediated_decay Mus_musculus 8e-38 163
ENSMUST00000130741 Ppp2r4-010 processed_transcript Mus_musculus 3e-37 161
ENSMUST00000159932 Ppp2r4-014 processed_transcript Mus_musculus 3e-27 128

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