C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: one cut homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119547 ONECUT2 9606 + 18:57435685-57491297 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000481727 ONECUT2-002 57444376-57476760 processed_transcript
  ENST00000491143 ONECUT2-001 57435685-57491297 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonKidneyLiverLungOvaryPlacentaTestisENST00000491143
Transcript ID Adipose Adrenal Bladder Brain Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000491143 0.001±0.00 0.001±0.00 0.018±0.00 0.098±0.03 0.028±0.00 1.067±1.02 0.444±0.44 0.073±0.00 0.057±0.00 0.004±0.00 0.099±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006OB CIL_0006OB_0001 CGP 18:57350813-57491297
CIL_0006O8 CIL_0006O8_0001 CGP 18:57435685-57586772

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001889 IEA liver development
GO:0001952 IEA regulation of cell-matrix adhesion
GO:0002064 IEA epithelial cell development
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0009653 IEA anatomical structure morphogenesis
GO:0009887 TAS organ morphogenesis
GO:0030335 IEA positive regulation of cell migration
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031016 IEA pancreas development
GO:0031018 IEA endocrine pancreas development
GO:0042384 IEA cilium assembly
GO:0045165 IEA cell fate commitment
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048935 IEA peripheral nervous system neuron development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090387 ONECUT2 one cut homeobox 2 protein_coding Danio_rerio
ENSMUSG00000045991 Onecut2 one cut domain, family member 2 protein_coding Mus_musculus

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