C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: one cut domain, family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045991 Onecut2 10090 + 18:64340364-64398488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000115145 Onecut2-201 64340364-64398486 protein_coding
  ENSMUST00000175965 Onecut2-001 64340364-64398488 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000115145ENSMUST00000175965
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000115145 0.002±0.00 0.029±0.01 0.003±0.00 0.121±0.00 0.003±0.00 0.008±0.00 0.005±0.00 0.003±0.00 2.066±1.62 0.001±0.00 0.714±0.30 0.043±0.04 0.008±0.01
ENSMUST00000175965 0.002±0.00 0.029±0.01 0.003±0.00 0.354±0.23 0.003±0.00 0.008±0.00 0.005±0.00 0.003±0.00 1.799±1.20 0.001±0.00 0.809±0.54 0.043±0.04 0.008±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006OB CIL_0006OB_0002 CGP 18:64254359-64398488
CIL_0006O8 CIL_0006O8_0002 CGP 18:64340364-64489066

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001889 IGI liver development
GO:0001952 IGI regulation of cell-matrix adhesion
GO:0002064 IMP epithelial cell development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0009653 IMP anatomical structure morphogenesis
GO:0030335 IGI positive regulation of cell migration
GO:0030512 IGI negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031016 IGI pancreas development
GO:0031018 IGI endocrine pancreas development
GO:0042384 IMP cilium assembly
GO:0045165 IGI cell fate commitment
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048935 IMP peripheral nervous system neuron development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090387 ONECUT2 one cut homeobox 2 protein_coding Danio_rerio
ENSG00000119547 ONECUT2 one cut homeobox 2 protein_coding Homo_sapiens

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