C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119919 NKX2-3 9606 + 10:99532933-99536524 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344586 NKX2-3-001 99532933-99536524 protein_coding
  ENST00000622383 NKX2-3-201 99532953-99536521 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonOvaryTestisENST00000622383
Transcript ID Adrenal Breast Colon Ovary Testis
ENST00000622383 0.032±0.00 1.539±0.00 11.791±10.21 0.099±0.07 0.140±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00054T CIL_00054T_0001 CGP 10:99396870-99536524
CIL_00054S CIL_00054S_0001 CGP 10:99532933-99620609

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001776 IEA leukocyte homeostasis
GO:0002317 IEA plasma cell differentiation
GO:0003674 ND molecular_function
GO:0003677 IEA DNA binding
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006641 IEA triglyceride metabolic process
GO:0006955 IEA immune response
GO:0008150 ND biological_process
GO:0009791 IEA post-embryonic development
GO:0022612 IEA gland morphogenesis
GO:0030183 IEA B cell differentiation
GO:0030225 IEA macrophage differentiation
GO:0042127 IEA regulation of cell proliferation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043367 IEA CD4-positive, alpha-beta T cell differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048535 IEA lymph node development
GO:0048536 IEA spleen development
GO:0048537 IEA mucosal-associated lymphoid tissue development
GO:0048541 IEA Peyer's patch development
GO:0048565 IEA digestive tract development
GO:0048621 IEA post-embryonic digestive tract morphogenesis
GO:0050900 IEA leukocyte migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039095 nkx2.3 NK2 transcription factor related 3 protein_coding Danio_rerio
ENSMUSG00000044220 Nkx2-3 NK2 homeobox 3 protein_coding Mus_musculus

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