C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044220 Nkx2-3 10090 + 19:43612325-43615892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000057178 Nkx2-3-001 43612325-43615892 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonLiverLungOvaryPlacentaTestisENSMUST00000057178
Transcript ID Adrenal Bladder Brain Breast Colon Liver Lung Ovary Placenta Testis
ENSMUST00000057178 0.014±0.00 0.010±0.00 0.596±0.30 0.086±0.00 8.823±1.68 0.071±0.04 0.021±0.01 0.033±0.00 0.939±0.83 0.042±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00054T CIL_00054T_0002 CGP 19:43499752-43615892
CIL_00054S CIL_00054S_0002 CGP 19:43612325-43674881

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001776 IMP leukocyte homeostasis
GO:0002317 IMP plasma cell differentiation
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006641 IMP triglyceride metabolic process
GO:0006955 IMP immune response
GO:0009791 IMP post-embryonic development
GO:0022612 IMP gland morphogenesis
GO:0030183 IMP B cell differentiation
GO:0030225 IMP macrophage differentiation
GO:0042127 IMP regulation of cell proliferation
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0043367 IMP CD4-positive, alpha-beta T cell differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048535 IMP lymph node development
GO:0048536 IMP spleen development
GO:0048537 IMP mucosal-associated lymphoid tissue development
GO:0048541 IMP Peyer's patch development
GO:0048565 IMP digestive tract development
GO:0048621 IMP post-embryonic digestive tract morphogenesis
GO:0050900 IMP leukocyte migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039095 nkx2.3 NK2 transcription factor related 3 protein_coding Danio_rerio
ENSG00000119919 NKX2-3 NK2 homeobox 3 protein_coding Homo_sapiens

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