C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, nicotinic, alpha 2 (neuronal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120903 CHRNA2 9606 - 8:27459762-27479883 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000240132 CHRNA2-004 27461603-27479261 protein_coding
  ENST00000407991 CHRNA2-201 27459762-27479296 protein_coding
  ENST00000518712 CHRNA2-009 27469812-27478929 protein_coding
  ENST00000520208 CHRNA2-010 27471002-27479857 protein_coding
  ENST00000520600 CHRNA2-002 27460576-27467517 retained_intron
  ENST00000520650 CHRNA2-007 27469832-27479013 retained_intron
  ENST00000520933 CHRNA2-001 27459778-27471212 protein_coding
  ENST00000521921 CHRNA2-008 27469905-27475502 protein_coding
  ENST00000522008 CHRNA2-012 27463628-27469408 retained_intron
  ENST00000523529 CHRNA2-006 27461098-27471183 retained_intron
  ENST00000523695 CHRNA2-005 27461098-27479214 nonsense_mediated_decay
  ENST00000524096 CHRNA2-011 27469349-27479883 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastKidneyLiverLungMusclePlacentaTestisENST00000240132ENST00000407991ENST00000520600ENST00000520650ENST00000521921ENST00000523529
Transcript ID Adipose Adrenal Bladder Brain Breast Kidney Liver Lung Muscle Placenta Testis
ENST00000240132 N/A N/A N/A 0.104±0.00 N/A N/A 0.034±0.00 N/A N/A 0.054±0.00 N/A
ENST00000407991 N/A 0.009±0.00 N/A N/A 0.006±0.00 N/A N/A N/A 0.010±0.00 N/A N/A
ENST00000520600 0.014±0.00 0.021±0.00 N/A N/A N/A 0.901±0.00 N/A N/A N/A N/A 0.066±0.00
ENST00000520650 N/A N/A N/A N/A N/A N/A N/A 0.036±0.00 N/A N/A N/A
ENST00000521921 N/A N/A 0.316±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000523529 N/A N/A N/A N/A N/A N/A N/A 0.036±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004889 IDA acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005892 IDA acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 NAS:IEA ion transport
GO:0006812 IDA cation transport
GO:0007165 IDA signal transduction
GO:0007268 TAS synaptic transmission
GO:0008144 IEA drug binding
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0042166 IEA acetylcholine binding
GO:0045211 IEA postsynaptic membrane
GO:0051291 IEA protein heterooligomerization
GO:0071944 IEA cell periphery
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006602 chrna2a cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) protein_coding Danio_rerio
ENSDARG00000057025 chrna2b cholinergic receptor, nicotinic, alpha polypeptide 2b (neuronal) protein_coding Danio_rerio
ENSMUSG00000022041 Chrna2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) protein_coding Mus_musculus

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