C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha 2 (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000240132 CHRNA2-004 ENSG00000120903 9606 - 8:27461603-27479261 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverPlacentaENST00000240132
Transcript ID Brain Liver Placenta
ENST00000240132 0.104±0.00 0.034±0.00 0.054±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004889 IDA acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005892 IDA acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 NAS:IEA ion transport
GO:0006812 IDA cation transport
GO:0007165 IDA signal transduction
GO:0007268 TAS synaptic transmission
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0045211 IEA postsynaptic membrane
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022620 Chrna2-001 protein_coding Mus_musculus 0 1399
ENSMUST00000067120 Chrna4-001 protein_coding Mus_musculus 0 830
ENSMUST00000108851 Chrna4-002 protein_coding Mus_musculus 0 830
ENSDART00000033947 chrna2a-001 protein_coding Danio_rerio 0 719
ENSDART00000079613 chrna2b-201 protein_coding Danio_rerio 0 699
ENSDART00000136317 chrna2b-001 protein_coding Danio_rerio 0 699
ENSMUST00000033882 Chrna6-201 protein_coding Mus_musculus 0 294
ENSMUST00000029562 Chrnb2-201 protein_coding Mus_musculus 0 226
ENSMUST00000135766 Chrna4-004 nonsense_mediated_decay Mus_musculus 4e-35 154

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