C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aconitase 1, soluble
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122729 ACO1 9606 + 9:32384603-32454769 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309951 ACO1-001 32384620-32454769 protein_coding
  ENST00000379923 ACO1-002 32384620-32450836 protein_coding
  ENST00000541043 ACO1-201 32384603-32450832 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309951ENST00000379923ENST00000541043
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309951 N/A 1.043±0.00 0.975±0.00 0.435±0.17 4.441±3.62 0.920±0.00 N/A 2.421±0.33 N/A N/A 0.193±0.00 0.744±0.00 0.784±0.00 0.855±0.14
ENST00000379923 45.447±0.00 12.019±0.00 6.775±0.00 4.001±1.56 36.352±29.41 10.588±4.11 5.518±1.49 27.386±4.08 22.573±18.09 4.061±0.31 6.968±5.49 9.489±4.30 12.622±2.67 12.482±1.92
ENST00000541043 N/A N/A 5.330±0.00 N/A N/A N/A 13.524±0.00 N/A N/A 3.792±0.00 N/A 7.309±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000437 CIL_000437_0001 CGP 9:32384603-32526324

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 NAS RNA binding
GO:0003994 IEA:IDA aconitate hydratase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005829 IDA cytosol
GO:0006099 IEA tricarboxylic acid cycle
GO:0006101 IDA citrate metabolic process
GO:0006417 IEA regulation of translation
GO:0006879 IEA cellular iron ion homeostasis
GO:0008152 IEA metabolic process
GO:0009791 IEA post-embryonic development
GO:0010040 IEA:IDA response to iron(II) ion
GO:0010468 IEA regulation of gene expression
GO:0030350 IDA iron-responsive element binding
GO:0046872 IEA metal ion binding
GO:0050892 IEA intestinal absorption
GO:0051539 IEA:IDA 4 iron, 4 sulfur cluster binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026376 aco1 aconitase 1, soluble protein_coding Danio_rerio
ENSMUSG00000028405 Aco1 aconitase 1 protein_coding Mus_musculus

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