C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aconitase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028405 Aco1 10090 + 4:40143081-40198338 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102973 Aco1-001 40143081-40198338 protein_coding
  ENSMUST00000135787 Aco1-003 40190530-40196404 processed_transcript
  ENSMUST00000142360 Aco1-004 40166877-40175866 processed_transcript
  ENSMUST00000152911 Aco1-002 40163719-40169360 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102973
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102973 43.053±21.32 16.910±2.51 24.933±2.48 13.393±4.95 26.601±9.72 6.655±0.69 6.507±1.26 42.129±4.77 22.772±7.65 11.207±2.44 3.741±0.37 19.789±13.37 36.166±6.56 2.126±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000437 CIL_000437_0002 CGP 4:40143081-40239828

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003994 ISS aconitate hydratase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0006099 IEA tricarboxylic acid cycle
GO:0006101 ISS citrate metabolic process
GO:0006417 IMP regulation of translation
GO:0006879 IGI cellular iron ion homeostasis
GO:0009791 IGI post-embryonic development
GO:0010040 ISS response to iron(II) ion
GO:0010468 IGI regulation of gene expression
GO:0030350 ISS iron-responsive element binding
GO:0046872 IEA metal ion binding
GO:0050892 IGI intestinal absorption
GO:0051539 ISS 4 iron, 4 sulfur cluster binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026376 aco1 aconitase 1, soluble protein_coding Danio_rerio
ENSG00000122729 ACO1 aconitase 1, soluble protein_coding Homo_sapiens

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