C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prolyl 4-hydroxylase, alpha polypeptide I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122884 P4HA1 9606 - 10:73007217-73096974 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263556 P4HA1-201 73007224-73096974 protein_coding
  ENST00000307116 P4HA1-001 73007217-73096850 protein_coding
  ENST00000373008 P4HA1-002 73007217-73096850 protein_coding
  ENST00000394890 P4HA1-202 73007224-73096974 protein_coding
  ENST00000440381 P4HA1-203 73007224-73096974 protein_coding
  ENST00000464310 P4HA1-004 73009640-73016861 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307116ENST00000373008ENST00000464310
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307116 5.909±0.00 3.396±0.00 N/A 3.982±0.00 3.801±0.00 6.975±0.00 5.568±4.04 4.643±0.00 4.922±3.31 3.747±0.00 19.672±0.00 11.101±4.20 11.599±4.39 6.896±1.70
ENST00000373008 2.828±0.00 3.164±0.00 2.656±0.00 2.088±0.05 7.143±3.21 13.402±10.33 8.529±3.73 6.445±0.00 3.886±2.21 13.021±0.27 14.193±0.00 8.164±1.18 9.499±2.34 6.626±2.00
ENST00000464310 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 27.972±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QA CIL_0008QA_0001 VISTA 10:72591086-73192639

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004656 IEA procollagen-proline 4-dioxygenase activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI:IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005783 IDA:IEA endoplasmic reticulum
GO:0016020 IDA membrane
GO:0016222 IEA procollagen-proline 4-dioxygenase complex
GO:0016491 IEA oxidoreductase activity
GO:0016702 IEA oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018401 IEA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0030199 IEA collagen fibril organization
GO:0031418 IEA L-ascorbic acid binding
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071082 p4ha1b prolyl 4-hydroxylase, alpha polypeptide I b protein_coding Danio_rerio
ENSMUSG00000019916 P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide protein_coding Mus_musculus

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