C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019916 P4ha1 10090 + 10:59323296-59373304 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000009789 P4ha1-001 59323296-59373304 protein_coding
  ENSMUST00000092512 P4ha1-003 59323364-59371956 protein_coding
  ENSMUST00000105466 P4ha1-002 59323368-59372251 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000009789ENSMUST00000092512ENSMUST00000105466
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000009789 1.909±0.74 1.230±0.26 4.022±0.12 1.183±0.48 1.582±0.28 1.031±0.21 2.048±0.16 2.388±0.42 0.864±0.20 2.758±0.32 1.491±0.37 3.119±0.73 6.056±3.20 0.695±0.22
ENSMUST00000092512 5.222±1.97 7.328±2.06 6.049±0.28 4.238±2.39 3.891±0.90 3.013±0.70 5.431±0.45 8.151±0.97 2.117±0.63 8.111±0.92 2.026±0.51 7.562±4.86 15.519±4.83 2.288±0.76
ENSMUST00000105466 5.149±1.61 4.504±2.61 7.105±1.07 4.202±4.05 6.543±1.90 3.496±0.83 4.683±1.38 5.134±0.58 2.252±1.08 8.281±1.46 4.392±0.85 13.967±5.04 35.065±24.56 1.674±0.68

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QA CIL_0008QA_0002 VISTA 10:59142760-59744333

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004656 IMP procollagen-proline 4-dioxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IEA mitochondrion
GO:0016020 IEA membrane
GO:0016222 IDA procollagen-proline 4-dioxygenase complex
GO:0016702 IEA oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0018401 IDA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0030199 IMP collagen fibril organization
GO:0031418 IEA L-ascorbic acid binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071082 p4ha1b prolyl 4-hydroxylase, alpha polypeptide I b protein_coding Danio_rerio
ENSG00000122884 P4HA1 prolyl 4-hydroxylase, alpha polypeptide I protein_coding Homo_sapiens

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