C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396148 CDKN2C-201 ENSG00000123080 9606 + 1:50968695-50974633 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000396148
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000396148 5.519±0.00 3.171±0.00 0.471±0.00 3.156±2.52 15.990±15.50 4.508±3.33 2.676±2.56 2.600±0.00 1.232±0.26 2.897±2.45 0.371±0.00 5.688±4.37 4.681±0.25 5.109±3.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AC CIL_0009AC_0001 VISTA 1:50399523-51001114
CIL_0006WA CIL_0006WA_0002 CGP 1:50439478-50974633

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000079 IDA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007050 IDA cell cycle arrest
GO:0008285 IDA negative regulation of cell proliferation
GO:0019901 IPI protein kinase binding
GO:0030308 IDA negative regulation of cell growth
GO:0042326 IDA negative regulation of phosphorylation
GO:0071901 IDA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000097921 Cdkn2c-001 protein_coding Mus_musculus 0 935
ENSMUST00000063531 Cdkn2c-002 protein_coding Mus_musculus 0 804

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