C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich splicing factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124193 SRSF6 9606 + 20:43457928-43464247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000244020 SRSF6-001 43457928-43464247 protein_coding
  ENST00000483871 SRSF6-002 43457928-43461334 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000244020ENST00000483871
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000244020 N/A 4.868±0.00 4.639±0.00 9.254±0.00 5.514±0.00 1.568±0.00 3.572±0.00 N/A 5.785±0.00 0.892±0.00 6.513±2.49 3.494±2.52 N/A
ENST00000483871 4.229±0.00 19.393±0.00 9.697±0.00 28.921±0.00 18.687±11.15 6.220±0.13 19.183±1.43 14.049±2.78 14.525±5.93 5.995±3.13 36.233±10.68 14.940±1.88 34.915±15.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004E4 CIL_0004E4_0001 CGP 20:42072752-43464247
CIL_00044L CIL_00044L_0001 CGP 20:43457928-43550950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000380 IDA alternative mRNA splicing, via spliceosome
GO:0000381 IDA regulation of alternative mRNA splicing, via spliceosome
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003723 IDA RNA binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006376 IMP mRNA splice site selection
GO:0006406 TAS mRNA export from nucleus
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0010837 IMP regulation of keratinocyte proliferation
GO:0016607 IDA nuclear speck
GO:0031124 TAS mRNA 3'-end processing
GO:0036002 IDA pre-mRNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045617 IMP negative regulation of keratinocyte differentiation
GO:0048025 IDA negative regulation of mRNA splicing, via spliceosome
GO:0060501 IDA positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060548 IDA negative regulation of cell death
GO:0061041 IMP regulation of wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013729 srsf6a serine/arginine-rich splicing factor 6a protein_coding Danio_rerio
ENSDARG00000016783 srsf6b serine/arginine-rich splicing factor 6b protein_coding Danio_rerio
ENSMUSG00000016921 Srsf6 serine/arginine-rich splicing factor 6 protein_coding Mus_musculus

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