C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: triggering receptor expressed on myeloid cells 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124731 TREM1 9606 - 6:41267926-41286719 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000244709 TREM1-001 41275204-41286719 protein_coding
  ENST00000334475 TREM1-002 41275621-41286682 protein_coding
  ENST00000586287 TREM1-005 41282254-41286682 retained_intron
  ENST00000589614 TREM1-007 41267926-41286665 protein_coding
  ENST00000589695 TREM1-006 41275986-41281234 retained_intron
  ENST00000589882 TREM1-004 41280191-41282066 retained_intron
  ENST00000591620 TREM1-003 41279539-41286682 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000244709ENST00000334475ENST00000586287ENST00000589614ENST00000589695ENST00000589882ENST00000591620
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000244709 0.653±0.00 N/A 0.124±0.09 0.178±0.10 0.092±0.00 0.048±0.00 0.227±0.07 0.135±0.04 3.143±1.46 0.060±0.00 4.078±4.67 2.105±0.71 0.156±0.00
ENST00000334475 0.573±0.00 0.147±0.00 0.675±0.00 0.280±0.00 0.162±0.00 0.165±0.00 N/A 0.219±0.00 7.112±0.00 0.148±0.00 N/A N/A 0.099±0.00
ENST00000586287 N/A N/A 0.037±0.00 0.330±0.00 0.572±0.00 N/A 0.232±0.00 0.312±0.00 8.296±5.02 0.504±0.00 7.237±0.00 4.842±0.00 N/A
ENST00000589614 1.450±0.00 N/A 0.271±0.00 0.193±0.00 N/A 0.251±0.00 0.395±0.00 N/A 8.835±4.89 N/A 5.618±3.97 3.592±1.03 0.282±0.16
ENST00000589695 N/A 0.158±0.00 N/A N/A N/A 0.203±0.00 N/A N/A 35.084±0.00 0.324±0.00 2.292±0.00 5.122±1.59 N/A
ENST00000589882 N/A 0.016±0.00 N/A 0.119±0.00 N/A 0.014±0.00 N/A 0.142±0.00 1.234±0.00 N/A N/A N/A N/A
ENST00000591620 N/A 0.014±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008F3 CIL_0008F3_0001 VISTA 6:41112821-41713777
CIL_0007QG CIL_0007QG_0001 VISTA 6:41166717-41767957
CIL_0008IB CIL_0008IB_0001 VISTA 6:41169077-41770286
CIL_0008XI CIL_0008XI_0001 VISTA 6:41187113-41790491
CIL_00093V CIL_00093V_0001 VISTA 6:41255486-41855939

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002374 IEA cytokine secretion involved in immune response
GO:0004872 TAS receptor activity
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0006959 TAS humoral immune response
GO:0007596 TAS blood coagulation
GO:0016021 IEA integral component of membrane
GO:0016477 IEA cell migration
GO:0030593 IEA neutrophil chemotaxis
GO:0035556 TAS intracellular signal transduction
GO:0042107 IEA cytokine metabolic process
GO:0045087 TAS innate immune response
GO:0050755 IEA chemokine metabolic process
GO:0050900 TAS leukocyte migration
GO:0070945 IEA neutrophil mediated killing of gram-negative bacterium
GO:0072672 IEA neutrophil extravasation
GO:0097110 IPI scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000042265 Trem1 triggering receptor expressed on myeloid cells 1 protein_coding Mus_musculus

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