C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paired box 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125618 PAX8 9606 - 2:113215997-113278950 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263334 PAX8-201 113215997-113278921 protein_coding
  ENST00000263335 PAX8-002 113215997-113278911 protein_coding
  ENST00000348715 PAX8-004 113215997-113278911 protein_coding
  ENST00000397647 PAX8-003 113215997-113278911 protein_coding
  ENST00000429538 PAX8-001 113215997-113278950 protein_coding
  ENST00000465084 PAX8-009 113218249-113235443 protein_coding
  ENST00000467778 PAX8-007 113241078-113278919 retained_intron
  ENST00000468980 PAX8-006 113218528-113241683 protein_coding
  ENST00000480684 PAX8-010 113218469-113220477 retained_intron
  ENST00000485840 PAX8-005 113225597-113237508 retained_intron
  ENST00000497038 PAX8-008 113218522-113241779 nonsense_mediated_decay
  ENST00000554352 PAX8-013 113235345-113236929 retained_intron
  ENST00000554830 PAX8-012 113241551-113278898 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyMuscleOvaryTestisENST00000348715ENST00000397647ENST00000429538ENST00000480684ENST00000485840
Transcript ID Colon Kidney Muscle Ovary Testis
ENST00000348715 N/A 54.612±0.00 N/A N/A N/A
ENST00000397647 0.047±0.00 N/A N/A N/A N/A
ENST00000429538 N/A 35.326±0.00 N/A 5.147±0.00 4.684±0.00
ENST00000480684 N/A N/A 0.993±0.00 N/A N/A
ENST00000485840 N/A N/A N/A 5.245±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000196 CIL_000196_0001 CGP 2:113157325-113278950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001655 ISS urogenital system development
GO:0001656 IEA metanephros development
GO:0001658 IEP branching involved in ureteric bud morphogenesis
GO:0001822 IEP kidney development
GO:0001823 ISS mesonephros development
GO:0003337 IEP mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003677 IDA:IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0004996 TAS thyroid-stimulating hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007417 IEP central nervous system development
GO:0009653 TAS anatomical structure morphogenesis
GO:0030154 IEA cell differentiation
GO:0030878 IEP thyroid gland development
GO:0038194 TAS thyroid-stimulating hormone signaling pathway
GO:0039003 ISS pronephric field specification
GO:0042472 ISS inner ear morphogenesis
GO:0042981 ISS regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048793 ISS pronephros development
GO:0071371 IDA cellular response to gonadotropin stimulus
GO:0071599 IEP otic vesicle development
GO:0072050 IEA S-shaped body morphogenesis
GO:0072073 IEA kidney epithelium development
GO:0072108 ISS positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0072164 IEA mesonephric tubule development
GO:0072207 IEP metanephric epithelium development
GO:0072221 ISS metanephric distal convoluted tubule development
GO:0072278 IEP metanephric comma-shaped body morphogenesis
GO:0072284 IEP metanephric S-shaped body morphogenesis
GO:0072289 ISS metanephric nephron tubule formation
GO:0072305 ISS negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
GO:0072307 ISS regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090190 ISS positive regulation of branching involved in ureteric bud morphogenesis
GO:1900212 ISS negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:1900215 ISS negative regulation of apoptotic process involved in metanephric collecting duct development
GO:1900218 ISS negative regulation of apoptotic process involved in metanephric nephron tubule development
GO:2000594 ISS positive regulation of metanephric DCT cell differentiation
GO:2000611 IMP positive regulation of thyroid hormone generation
GO:2000612 IMP regulation of thyroid-stimulating hormone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015879 pax8 paired box gene 8 protein_coding Danio_rerio
ENSMUSG00000026976 Pax8 paired box 8 protein_coding Mus_musculus

Loading