C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paired box 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263335 PAX8-002 ENSG00000125618 9606 - 2:113215997-113278911 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000196 CIL_000196_0001 CGP 2:113157325-113278950

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001655 ISS urogenital system development
GO:0001658 IEP branching involved in ureteric bud morphogenesis
GO:0001822 IEP kidney development
GO:0001823 ISS mesonephros development
GO:0003337 IEP mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003677 IDA:IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0004996 TAS thyroid-stimulating hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007417 IEP central nervous system development
GO:0009653 TAS anatomical structure morphogenesis
GO:0030878 IEP thyroid gland development
GO:0038194 TAS thyroid-stimulating hormone signaling pathway
GO:0039003 ISS pronephric field specification
GO:0042472 ISS inner ear morphogenesis
GO:0042981 ISS regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048793 ISS pronephros development
GO:0071371 IDA cellular response to gonadotropin stimulus
GO:0071599 IEP otic vesicle development
GO:0072108 ISS positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0072207 IEP metanephric epithelium development
GO:0072221 ISS metanephric distal convoluted tubule development
GO:0072278 IEP metanephric comma-shaped body morphogenesis
GO:0072284 IEP metanephric S-shaped body morphogenesis
GO:0072289 ISS metanephric nephron tubule formation
GO:0072305 ISS negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
GO:0072307 ISS regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090190 ISS positive regulation of branching involved in ureteric bud morphogenesis
GO:1900212 ISS negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:1900215 ISS negative regulation of apoptotic process involved in metanephric collecting duct development
GO:1900218 ISS negative regulation of apoptotic process involved in metanephric nephron tubule development
GO:2000594 ISS positive regulation of metanephric DCT cell differentiation
GO:2000611 IMP positive regulation of thyroid hormone generation
GO:2000612 IMP regulation of thyroid-stimulating hormone secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000153601 Pax8-005 protein_coding Mus_musculus 0 1491
ENSMUST00000028355 Pax8-001 protein_coding Mus_musculus 0 1083
ENSMUST00000136228 Pax8-004 protein_coding Mus_musculus 0 1070
ENSMUST00000149294 Pax8-003 protein_coding Mus_musculus 0 1014
ENSMUST00000153535 Pax8-008 protein_coding Mus_musculus 0 708
ENSMUST00000133746 Pax8-009 processed_transcript Mus_musculus 0 424
ENSMUST00000149860 Pax8-007 retained_intron Mus_musculus 0 401
ENSMUST00000152614 Pax8-002 retained_intron Mus_musculus 7e-20 104

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