C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paired box 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026976 Pax8 10090 - 2:24420560-24475599 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028355 Pax8-001 24420560-24475599 protein_coding
  ENSMUST00000133746 Pax8-009 24442998-24445900 processed_transcript
  ENSMUST00000136228 Pax8-004 24429527-24475574 protein_coding
  ENSMUST00000149294 Pax8-003 24421520-24475097 protein_coding
  ENSMUST00000149860 Pax8-007 24421394-24423082 retained_intron
  ENSMUST00000152614 Pax8-002 24471885-24475574 retained_intron
  ENSMUST00000153535 Pax8-008 24441177-24475215 protein_coding
  ENSMUST00000153601 Pax8-005 24421531-24475564 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENSMUST00000028355ENSMUST00000149294ENSMUST00000149860ENSMUST00000153601
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENSMUST00000028355 4.739±3.33 0.014±0.00 0.629±0.71 0.029±0.00 0.229±0.00 23.219±2.04 0.019±0.01 6.634±2.45 2.940±3.64 0.475±0.45
ENSMUST00000149294 N/A N/A N/A N/A N/A N/A 0.052±0.03 N/A N/A 0.051±0.00
ENSMUST00000149860 N/A N/A N/A N/A N/A N/A 0.051±0.00 N/A N/A N/A
ENSMUST00000153601 N/A N/A N/A N/A N/A N/A 0.015±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000196 CIL_000196_0002 CGP 2:24367580-24475599

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000979 ISS RNA polymerase II core promoter sequence-specific DNA binding
GO:0001655 IGI urogenital system development
GO:0001656 IGI metanephros development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001822 IEA kidney development
GO:0001823 IMP mesonephros development
GO:0003337 IEA mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003677 ISS DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0005667 TAS transcription factor complex
GO:0006351 IDA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007417 IEP central nervous system development
GO:0009887 TAS organ morphogenesis
GO:0030154 IMP cell differentiation
GO:0030878 IGI thyroid gland development
GO:0039003 IEP pronephric field specification
GO:0042472 IGI inner ear morphogenesis
GO:0042981 IMP regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 ISO positive regulation of transcription from RNA polymerase II promoter
GO:0048793 IMP pronephros development
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0071599 IEA otic vesicle development
GO:0072050 IEP S-shaped body morphogenesis
GO:0072073 IEP kidney epithelium development
GO:0072108 IMP positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0072164 IEP mesonephric tubule development
GO:0072207 IEA metanephric epithelium development
GO:0072221 IMP metanephric distal convoluted tubule development
GO:0072278 IEA metanephric comma-shaped body morphogenesis
GO:0072284 IEA metanephric S-shaped body morphogenesis
GO:0072289 IMP metanephric nephron tubule formation
GO:0072305 IMP negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
GO:0072307 IMP regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090190 IMP positive regulation of branching involved in ureteric bud morphogenesis
GO:1900212 IMP negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:1900215 IMP negative regulation of apoptotic process involved in metanephric collecting duct development
GO:1900218 IMP negative regulation of apoptotic process involved in metanephric nephron tubule development
GO:2000594 IMP positive regulation of metanephric DCT cell differentiation
GO:2000611 IMP positive regulation of thyroid hormone generation
GO:2000612 ISS regulation of thyroid-stimulating hormone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015879 pax8 paired box gene 8 protein_coding Danio_rerio
ENSG00000125618 PAX8 paired box 8 protein_coding Homo_sapiens

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