C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125675 GRIA3 9606 + X:123184153-123490915 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000460123 GRIA3-003 123482723-123488942 processed_transcript
  ENST00000477389 GRIA3-005 123354909-123361323 processed_transcript
  ENST00000479118 GRIA3-004 123184560-123253702 processed_transcript
  ENST00000541091 GRIA3-002 123184483-123483046 protein_coding
  ENST00000611689 GRIA3-006 123184299-123204683 protein_coding
  ENST00000616590 GRIA3-007 123184153-123204683 protein_coding
  ENST00000620443 GRIA3-001 123184483-123490915 protein_coding
  ENST00000620581 GRIA3-201 123184371-123488736 protein_coding
  ENST00000622768 GRIA3-202 123184243-123490905 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000460123ENST00000479118ENST00000541091ENST00000611689ENST00000616590ENST00000620443ENST00000620581ENST00000622768
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000460123 N/A N/A N/A N/A N/A N/A N/A 0.734±0.00 N/A N/A N/A N/A N/A N/A
ENST00000479118 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.132±0.00 N/A N/A N/A
ENST00000541091 0.020±0.00 0.145±0.00 0.229±0.00 4.035±0.00 0.110±0.00 0.246±0.16 0.046±0.00 N/A 0.265±0.01 N/A N/A 0.245±0.23 1.192±0.00 0.523±0.00
ENST00000611689 N/A N/A N/A N/A N/A N/A N/A 0.418±0.00 N/A 0.273±0.00 N/A N/A N/A N/A
ENST00000616590 N/A N/A N/A N/A N/A N/A N/A N/A 0.979±0.00 N/A N/A N/A N/A N/A
ENST00000620443 0.039±0.00 0.114±0.00 0.064±0.00 8.081±1.90 0.104±0.03 0.075±0.00 N/A N/A 0.076±0.00 N/A 0.037±0.03 0.151±0.14 N/A 0.350±0.16
ENST00000620581 N/A N/A N/A N/A 0.153±0.00 0.481±0.00 0.526±0.00 N/A N/A N/A N/A 0.048±0.00 0.217±0.00 0.428±0.00
ENST00000622768 N/A N/A N/A 6.243±3.76 N/A N/A N/A 0.282±0.00 N/A 0.050±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001U7 CIL_0001U7_0001 CGP X:123184153-123733056

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004971 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006810 TAS transport
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032737 gria3a glutamate receptor, ionotropic, AMPA 3a protein_coding Danio_rerio
ENSDARG00000037498 gria3b glutamate receptor, ionotrophic, AMPA 3b protein_coding Danio_rerio
ENSMUSG00000001986 Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) protein_coding Mus_musculus

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