C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA3 (alpha 3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001986 Gria3 10090 + X:41400854-41678601 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076349 Gria3-001 41401304-41678601 protein_coding
  ENSMUST00000115103 Gria3-004 41401128-41676585 protein_coding
  ENSMUST00000124169 Gria3-007 41402740-41478661 protein_coding
  ENSMUST00000126843 Gria3-008 41610197-41621262 retained_intron
  ENSMUST00000128197 Gria3-005 41400854-41613099 retained_intron
  ENSMUST00000139965 Gria3-002 41401436-41678598 nonsense_mediated_decay
  ENSMUST00000148212 Gria3-006 41401482-41613554 retained_intron
  ENSMUST00000156721 Gria3-003 41401398-41676592 retained_intron
  ENSMUST00000165288 Gria3-201 41401565-41672464 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076349ENSMUST00000124169ENSMUST00000128197ENSMUST00000139965ENSMUST00000148212ENSMUST00000156721ENSMUST00000165288
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076349 0.626±0.02 2.004±0.31 1.624±0.32 7.214±1.22 0.810±0.25 0.534±0.23 0.158±0.02 0.927±0.38 0.629±0.13 1.742±0.42 0.164±0.11 0.905±0.28 0.310±0.18 0.174±0.00
ENSMUST00000124169 N/A N/A N/A N/A N/A 1.833±0.06 1.130±0.00 N/A N/A N/A N/A 6.181±0.00 N/A 1.065±0.00
ENSMUST00000128197 0.179±0.10 1.263±0.36 0.552±0.02 N/A 0.458±0.10 0.237±0.06 0.103±0.00 0.401±0.08 0.145±0.08 0.730±0.16 0.045±0.01 0.625±0.20 0.077±0.05 0.084±0.03
ENSMUST00000139965 0.517±0.14 4.142±0.02 N/A 15.095±0.00 0.671±0.11 0.324±0.19 0.225±0.02 0.947±0.56 0.041±0.02 1.054±0.30 0.071±0.00 1.172±0.59 0.058±0.04 0.108±0.04
ENSMUST00000148212 0.682±0.10 N/A 0.572±0.04 N/A 0.367±0.02 0.224±0.06 0.088±0.02 0.274±0.00 0.028±0.00 0.774±0.18 0.075±0.02 0.536±0.00 0.175±0.04 N/A
ENSMUST00000156721 N/A N/A N/A N/A N/A N/A N/A N/A 0.071±0.05 N/A N/A N/A N/A 0.031±0.00
ENSMUST00000165288 0.573±0.00 N/A N/A 26.434±0.00 N/A N/A N/A N/A 0.183±0.00 N/A N/A 2.050±0.00 0.097±0.00 0.104±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001U7 CIL_0001U7_0002 CGP X:41400854-41920674

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004971 IBA:ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0016020 IDA membrane
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0032281 IDA:ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032737 gria3a glutamate receptor, ionotropic, AMPA 3a protein_coding Danio_rerio
ENSDARG00000037498 gria3b glutamate receptor, ionotrophic, AMPA 3b protein_coding Danio_rerio
ENSG00000125675 GRIA3 glutamate receptor, ionotropic, AMPA 3 protein_coding Homo_sapiens

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