C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: argonaute RISC catalytic component 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126070 AGO3 9606 + 1:35930718-36072500 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246314 AGO3-002 35931258-36056462 protein_coding
  ENST00000324350 AGO3-001 35930718-35983409 protein_coding
  ENST00000373191 AGO3-003 35931078-36072500 protein_coding
  ENST00000397828 AGO3-201 35931082-35982652 protein_coding
  ENST00000471099 AGO3-007 36043264-36055262 retained_intron
  ENST00000491443 AGO3-004 35966955-35973592 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000246314ENST00000324350ENST00000373191
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000246314 N/A N/A 3.073±0.00 2.227±0.00 1.126±0.00 N/A N/A N/A 0.897±0.00 2.909±0.00 0.557±0.09 2.565±0.00
ENST00000324350 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.208±0.00 N/A 5.036±0.00
ENST00000373191 0.978±0.00 1.480±0.00 1.473±0.00 0.587±0.00 0.514±0.12 0.239±0.00 1.105±0.00 0.981±0.00 0.293±0.00 0.851±0.26 0.655±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0003743 IEA translation initiation factor activity
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0006402 IDA mRNA catabolic process
GO:0006413 IEA translational initiation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016442 IEA RISC complex
GO:0035068 IEA micro-ribonucleoprotein complex
GO:0035198 IEA miRNA binding
GO:0035278 IDA negative regulation of translation involved in gene silencing by miRNA
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0072091 IMP regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059888 argonaute RISC catalytic component 3 protein_coding Danio_rerio
ENSDARG00000063079 ago3b argonaute RISC catalytic component 3b protein_coding Danio_rerio
ENSMUSG00000028842 Ago3 argonaute RISC catalytic subunit 3 protein_coding Mus_musculus

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