C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: argonaute RISC catalytic subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028842 Ago3 10090 - 4:126331704-126429556 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069097 Ago3-001 126332732-126429556 protein_coding
  ENSMUST00000123233 Ago3-006 126407696-126429541 processed_transcript
  ENSMUST00000127831 Ago3-003 126345577-126350902 protein_coding
  ENSMUST00000132123 Ago3-002 126331704-126350320 protein_coding
  ENSMUST00000151179 Ago3-004 126375678-126404294 processed_transcript
  ENSMUST00000155645 Ago3-005 126397956-126404335 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069097ENSMUST00000123233
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069097 1.524±0.58 1.438±0.19 2.357±0.11 1.945±1.11 1.528±0.19 1.085±0.12 0.960±0.07 1.223±0.20 0.766±0.22 2.004±0.12 0.368±0.17 1.813±0.57 1.093±0.12 0.883±0.07
ENSMUST00000123233 8.299±0.59 10.437±2.84 N/A N/A 9.885±2.57 5.457±2.09 N/A 4.941±0.26 1.584±0.10 7.684±1.72 N/A 12.982±5.15 N/A 6.207±0.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JR CIL_0002JR_0002 CGP 4:126331704-126468583

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IDA RNA binding
GO:0005737 IEA cytoplasm
GO:0006402 ISS mRNA catabolic process
GO:0016020 IEA membrane
GO:0016442 IEA RISC complex
GO:0035068 IDA micro-ribonucleoprotein complex
GO:0035198 IEA miRNA binding
GO:0035278 ISS negative regulation of translation involved in gene silencing by miRNA
GO:0044822 IEA poly(A) RNA binding
GO:0072091 IEA regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059888 argonaute RISC catalytic component 3 protein_coding Danio_rerio
ENSDARG00000063079 ago3b argonaute RISC catalytic component 3b protein_coding Danio_rerio
ENSG00000126070 AGO3 argonaute RISC catalytic component 3 protein_coding Homo_sapiens

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