C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ras homolog family member T1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126858 RHOT1 9606 + 17:32142454-32253374 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333942 RHOT1-001 32142454-32225770 protein_coding
  ENST00000354266 RHOT1-004 32142560-32225666 protein_coding
  ENST00000358365 RHOT1-002 32142466-32225727 protein_coding
  ENST00000394692 RHOT1-008 32142680-32225727 protein_coding
  ENST00000545287 RHOT1-015 32142537-32225113 protein_coding
  ENST00000578205 RHOT1-007 32142673-32225503 nonsense_mediated_decay
  ENST00000580392 RHOT1-012 32203937-32253374 protein_coding
  ENST00000580976 RHOT1-010 32142677-32199504 processed_transcript
  ENST00000581031 RHOT1-005 32142568-32225503 nonsense_mediated_decay
  ENST00000581094 RHOT1-006 32142630-32209738 protein_coding
  ENST00000581148 RHOT1-013 32206925-32211435 protein_coding
  ENST00000581567 RHOT1-011 32203860-32207541 retained_intron
  ENST00000582586 RHOT1-016 32209388-32242162 processed_transcript
  ENST00000582602 RHOT1-018 32202824-32211195 protein_coding
  ENST00000583994 RHOT1-003 32142475-32225727 nonsense_mediated_decay
  ENST00000584692 RHOT1-014 32206950-32224960 nonsense_mediated_decay
  ENST00000584852 RHOT1-017 32208302-32253374 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000333942ENST00000354266ENST00000358365ENST00000394692ENST00000545287ENST00000578205ENST00000581031ENST00000581094ENST00000583994
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000333942 2.682±0.00 N/A N/A 4.145±0.00 1.732±0.34 2.558±0.21 1.444±0.00 N/A N/A 2.305±0.00 N/A 3.771±0.79 2.824±0.18 2.069±0.00
ENST00000354266 N/A 0.959±0.00 N/A 3.048±0.95 2.459±0.00 4.183±0.00 5.811±0.00 3.923±0.00 1.134±0.00 2.587±0.00 2.432±0.00 2.519±0.05 N/A 2.843±0.89
ENST00000358365 N/A 1.846±0.00 N/A 4.741±0.00 1.815±0.00 2.986±0.00 3.220±0.00 2.391±0.00 1.553±0.00 1.300±0.00 N/A 1.992±0.15 0.813±0.00 4.011±0.00
ENST00000394692 N/A N/A 1.155±0.00 2.612±0.00 0.996±0.00 1.285±0.00 N/A 1.485±0.00 0.718±0.00 1.478±0.07 0.989±0.00 2.421±0.00 1.415±0.50 2.261±0.00
ENST00000545287 N/A N/A 2.556±0.00 2.212±0.00 1.776±0.00 1.826±0.00 3.411±0.00 N/A 6.658±0.00 2.661±0.00 N/A 2.613±0.53 2.200±0.00 2.297±0.00
ENST00000578205 1.666±0.00 1.044±0.00 N/A 3.341±0.00 1.507±0.11 1.679±0.00 N/A N/A 1.834±0.00 1.802±0.00 N/A 2.975±0.00 N/A N/A
ENST00000581031 2.457±0.00 1.498±0.00 N/A N/A N/A 1.945±0.00 2.934±0.00 1.456±0.00 N/A N/A 0.846±0.00 1.835±0.00 0.796±0.00 N/A
ENST00000581094 N/A N/A N/A N/A 0.880±0.00 N/A N/A N/A 1.448±0.00 2.066±0.00 N/A N/A N/A N/A
ENST00000583994 N/A N/A N/A N/A N/A 1.465±0.00 N/A N/A N/A N/A N/A N/A 0.737±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VO CIL_0000VO_0001 CGP 17:32142454-32324661

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003924 IEA GTPase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005739 IEA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA:TAS small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0019725 IEA:IMP cellular homeostasis
GO:0031307 IDA integral component of mitochondrial outer membrane
GO:0047497 IMP mitochondrion transport along microtubule
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097345 IMP mitochondrial outer membrane permeabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018130 rhot1a ras homolog gene family, member T1a protein_coding Danio_rerio
ENSDARG00000070316 rhot1b ras homolog gene family, member T1b protein_coding Danio_rerio
ENSDARG00000096023 RHOT1 (3 of 3) ras homolog family member T1 protein_coding Danio_rerio
ENSMUSG00000017686 Rhot1 ras homolog gene family, member T1 protein_coding Mus_musculus

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