C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129084 PSMA1 9606 - 11:14504874-14643635 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000396394 PSMA1-001 14504876-14520696 protein_coding
  ENST00000418988 PSMA1-002 14505064-14643617 protein_coding
  ENST00000524606 PSMA1-021 14504874-14511031 processed_transcript
  ENST00000526443 PSMA1-014 14514342-14520072 retained_intron
  ENST00000527632 PSMA1-020 14507587-14514002 retained_intron
  ENST00000528018 PSMA1-017 14610854-14643635 processed_transcript
  ENST00000528307 PSMA1-003 14504924-14520359 retained_intron
  ENST00000529524 PSMA1-018 14513664-14517673 retained_intron
  ENST00000530457 PSMA1-004 14504913-14520363 protein_coding
  ENST00000531023 PSMA1-007 14510914-14514293 retained_intron
  ENST00000531156 PSMA1-016 14514315-14520338 retained_intron
  ENST00000532256 PSMA1-010 14517949-14520382 protein_coding
  ENST00000533068 PSMA1-009 14517912-14520445 protein_coding
  ENST00000533331 PSMA1-012 14513460-14520380 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000396394ENST00000418988ENST00000531156
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000396394 42.884±0.00 53.084±0.00 3.517±0.00 25.329±16.34 49.482±0.00 42.320±0.00 40.872±0.00 42.542±0.00 44.989±0.00 50.328±0.00 28.182±19.75 39.936±16.84 53.168±16.19 51.011±0.00
ENST00000418988 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.677±0.00
ENST00000531156 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.968±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003PO CIL_0003PO_0001 CGP 11:14443440-14520344
CIL_0003ZT CIL_0003ZT_0001 CGP 11:14504874-14872044

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003723 TAS RNA binding
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005839 IEA:ISS proteasome core complex
GO:0005844 TAS polysome
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074076 psma1 proteasome (prosome, macropain) subunit, alpha type, 1 protein_coding Danio_rerio
ENSMUSG00000030751 Psma1 proteasome (prosome, macropain) subunit, alpha type 1 protein_coding Mus_musculus

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