C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030751 Psma1 10090 - 7:114264606-114276118 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033008 Psma1-001 114264606-114276118 protein_coding
  ENSMUST00000123801 Psma1-003 114273803-114276043 retained_intron
  ENSMUST00000135570 Psma1-004 114264795-114276026 processed_transcript
  ENSMUST00000154909 Psma1-002 114270489-114276054 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033008ENSMUST00000135570
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033008 71.157±1.98 28.962±3.95 86.195±16.36 61.103±30.22 46.725±11.10 46.819±1.81 67.937±5.77 62.979±5.20 94.459±28.88 56.890±5.31 41.975±1.72 31.039±19.76 99.216±37.07 21.567±7.73
ENSMUST00000135570 N/A 15.437±1.65 N/A 7.817±0.00 41.850±38.94 N/A 11.260±0.00 N/A N/A N/A N/A 25.426±8.29 27.874±9.37 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003PO CIL_0003PO_0002 CGP 7:114215559-114276118
CIL_0003ZT CIL_0003ZT_0002 CGP 7:114264606-114539251

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IDA proteasome complex
GO:0001530 IDA lipopolysaccharide binding
GO:0002376 IEA immune system process
GO:0002862 IMP negative regulation of inflammatory response to antigenic stimulus
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0005839 IDA proteasome core complex
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074076 psma1 proteasome (prosome, macropain) subunit, alpha type, 1 protein_coding Danio_rerio
ENSG00000129084 PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 protein_coding Homo_sapiens
ENSG00000256206 PSMA1 proteasome subunit alpha type-1 isoform 3 protein_coding Homo_sapiens

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