C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neural precursor cell expressed, developmentally down-regulated 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129559 NEDD8 9606 - 14:24216852-24232454 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000250495 NEDD8-001 24216852-24232454 protein_coding
  ENST00000396828 NEDD8-002 24216857-24232303 nonsense_mediated_decay
  ENST00000524927 NEDD8-004 24217716-24232354 protein_coding
  ENST00000526430 NEDD8-007 24217020-24232331 processed_transcript
  ENST00000527046 NEDD8-005 24216859-24232002 processed_transcript
  ENST00000531430 NEDD8-006 24216866-24232325 processed_transcript
  ENST00000533242 NEDD8-003 24226605-24232355 processed_transcript
  ENST00000560427 NEDD8-008 24216996-24218726 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000250495ENST00000531430
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000250495 147.769±0.00 367.500±0.00 21.197±0.00 191.596±132.26 106.746±80.09 138.916±0.00 100.481±83.50 233.636±197.10 70.138±53.53 325.983±0.00 40.754±19.57 188.238±141.05 305.196±102.39 235.553±0.00
ENST00000531430 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.866±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00029W CIL_00029W_0001 CGP 14:24213955-24232454
CIL_0002AC CIL_0002AC_0001 CGP 14:24216852-24239242

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006464 TAS cellular protein modification process
GO:0006508 TAS proteolysis
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008104 IEA protein localization
GO:0009653 TAS anatomical structure morphogenesis
GO:0014070 IEA response to organic cyclic compound
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045116 IDA protein neddylation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007989 nedd8 neural precursor cell expressed, developmentally down-regulated 8 protein_coding Danio_rerio
ENSMUSG00000010376 Nedd8 neural precursor cell expressed, developmentally down-regulated gene 8 protein_coding Mus_musculus

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