C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin I type 3 (cardiac)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129991 TNNI3 9606 - 19:55151767-55157773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344887 TNNI3-001 55151770-55157732 protein_coding
  ENST00000585806 TNNI3-007 55151767-55156481 retained_intron
  ENST00000586446 TNNI3-002 55156729-55157732 retained_intron
  ENST00000586669 TNNI3-004 55154110-55157282 processed_transcript
  ENST00000586858 TNNI3-005 55156275-55156792 protein_coding
  ENST00000587176 TNNI3-009 55154305-55157773 retained_intron
  ENST00000588882 TNNI3-006 55151771-55156725 protein_coding
  ENST00000589864 TNNI3-008 55151770-55154406 retained_intron
  ENST00000590463 TNNI3-003 55154746-55157716 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungMuscleOvaryPlacentaENST00000344887ENST00000585806ENST00000586669ENST00000588882ENST00000589864ENST00000590463
Transcript ID Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENST00000344887 N/A N/A 0.219±0.00 1632.066±966.73 N/A 0.485±0.00 N/A 3.221±0.00 10.778±13.43
ENST00000585806 0.658±0.00 0.173±0.00 N/A N/A N/A N/A 3.237±0.00 N/A N/A
ENST00000586669 N/A N/A N/A N/A 0.169±0.00 N/A N/A 0.348±0.00 3.714±0.00
ENST00000588882 N/A N/A N/A N/A N/A N/A N/A N/A 0.600±0.00
ENST00000589864 0.649±0.00 N/A N/A N/A 0.109±0.00 0.246±0.00 4.235±0.00 N/A N/A
ENST00000590463 N/A N/A N/A N/A N/A N/A N/A 0.254±0.00 2.838±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065K CIL_00065K_0001 CGP 19:55132794-55157773
CIL_0004TD CIL_0004TD_0001 CGP 19:55151767-55160671

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 ISS vasculogenesis
GO:0001980 ISS regulation of systemic arterial blood pressure by ischemic conditions
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005861 IDA:IEA troponin complex
GO:0006874 ISS cellular calcium ion homeostasis
GO:0006937 IEA regulation of muscle contraction
GO:0006940 IEA regulation of smooth muscle contraction
GO:0006941 IEA striated muscle contraction
GO:0007507 ISS heart development
GO:0019855 IPI calcium channel inhibitor activity
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0030016 IEA myofibril
GO:0030017 TAS sarcomere
GO:0030049 TAS muscle filament sliding
GO:0030172 IPI troponin C binding
GO:0031014 IPI troponin T binding
GO:0032780 IMP negative regulation of ATPase activity
GO:0043292 IEA contractile fiber
GO:0046872 IEA metal ion binding
GO:0048306 IPI calcium-dependent protein binding
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060047 IMP heart contraction
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000035458 Tnni3 troponin I, cardiac 3 protein_coding Mus_musculus

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