C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: troponin I type 3 (cardiac)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000344887 TNNI3-001 ENSG00000129991 9606 - 19:55151770-55157732 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartLungOvaryPlacentaENST00000344887
Transcript ID Colon Heart Lung Ovary Placenta
ENST00000344887 0.219±0.00 1632.066±966.73 0.485±0.00 3.221±0.00 10.778±13.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065K CIL_00065K_0001 CGP 19:55132794-55157773
CIL_0004TD CIL_0004TD_0001 CGP 19:55151767-55160671

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001570 ISS vasculogenesis
GO:0001980 ISS regulation of systemic arterial blood pressure by ischemic conditions
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005861 IDA:IEA troponin complex
GO:0006874 ISS cellular calcium ion homeostasis
GO:0006937 IEA regulation of muscle contraction
GO:0006940 IEA regulation of smooth muscle contraction
GO:0006941 IEA striated muscle contraction
GO:0007507 ISS heart development
GO:0019855 IPI calcium channel inhibitor activity
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0030016 IEA myofibril
GO:0030017 TAS sarcomere
GO:0030049 TAS muscle filament sliding
GO:0030172 IPI troponin C binding
GO:0031014 IPI troponin T binding
GO:0032780 IMP negative regulation of ATPase activity
GO:0043292 IEA contractile fiber
GO:0046872 IEA metal ion binding
GO:0048306 IPI calcium-dependent protein binding
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060047 IMP heart contraction
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098859 Tnni3-001 protein_coding Mus_musculus 0 782
ENSMUST00000126873 Tnni3-007 retained_intron Mus_musculus 0 510
ENSMUST00000132621 Tnni3-006 retained_intron Mus_musculus 0 398

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