C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin I, cardiac 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035458 Tnni3 10090 - 7:4518305-4524229 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000098859 Tnni3-001 4518305-4522528 protein_coding
  ENSMUST00000126873 Tnni3-007 4518308-4520567 retained_intron
  ENSMUST00000127736 Tnni3-005 4521042-4521984 retained_intron
  ENSMUST00000132621 Tnni3-006 4518305-4519764 retained_intron
  ENSMUST00000140424 Tnni3-002 4520438-4522794 protein_coding
  ENSMUST00000150166 Tnni3-003 4521341-4522492 retained_intron
  ENSMUST00000151844 Tnni3-004 4521899-4522442 processed_transcript
  ENSMUST00000154913 Tnni3-008 4520477-4524229 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000098859ENSMUST00000126873ENSMUST00000127736ENSMUST00000140424ENSMUST00000150166ENSMUST00000151844ENSMUST00000154913
Transcript ID Adrenal Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000098859 1.120±0.20 N/A N/A 1673.690±236.45 0.718±0.25 0.161±0.03 30.812±4.98 0.283±0.18 36.165±51.00 0.868±0.17 32.815±0.00
ENSMUST00000126873 N/A 1.041±0.00 N/A N/A N/A N/A N/A 0.374±0.16 54.662±6.87 0.798±0.27 N/A
ENSMUST00000127736 N/A N/A N/A N/A N/A 0.812±0.00 N/A N/A N/A N/A N/A
ENSMUST00000140424 1.854±0.05 N/A N/A N/A 1.069±0.00 0.414±0.09 125.320±50.19 N/A 86.361±18.12 0.832±0.00 N/A
ENSMUST00000150166 1.475±0.07 N/A 1.048±0.00 N/A N/A N/A N/A N/A 17.432±2.58 0.454±0.00 N/A
ENSMUST00000151844 N/A N/A N/A N/A N/A 0.727±0.41 N/A 0.318±0.04 108.670±18.93 N/A N/A
ENSMUST00000154913 N/A N/A N/A 4435.370±1718.43 0.851±0.27 N/A 92.623±17.88 0.145±0.00 20.797±4.21 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065K CIL_00065K_0002 CGP 7:4504570-4524229
CIL_0004TD CIL_0004TD_0002 CGP 7:4518305-4532453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IDA vasculogenesis
GO:0001980 IMP regulation of systemic arterial blood pressure by ischemic conditions
GO:0003779 IEA actin binding
GO:0005515 IEA protein binding
GO:0005737 ISO cytoplasm
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006937 IDA regulation of muscle contraction
GO:0006940 IEA regulation of smooth muscle contraction
GO:0006941 IDA striated muscle contraction
GO:0007507 IDA heart development
GO:0019855 IEA calcium channel inhibitor activity
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030016 IEA myofibril
GO:0030017 ISO sarcomere
GO:0030172 IEA troponin C binding
GO:0031014 IEA troponin T binding
GO:0032780 IEA negative regulation of ATPase activity
GO:0043292 IEA contractile fiber
GO:0046872 IEA metal ion binding
GO:0048306 IEA calcium-dependent protein binding
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis
GO:0060047 IEA heart contraction
GO:0060048 IEA cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000129991 TNNI3 troponin I type 3 (cardiac) protein_coding Homo_sapiens

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