C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: helicase with zinc finger 2, transcriptional coactivator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130589 HELZ2 9606 - 20:63558086-63574239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370082 HELZ2-004 63570139-63574239 retained_intron
  ENST00000427522 HELZ2-001 63558086-63568074 protein_coding
  ENST00000454223 HELZ2-006 63567441-63568605 processed_transcript
  ENST00000467148 HELZ2-003 63559202-63572455 protein_coding
  ENST00000478861 HELZ2-002 63558662-63561605 processed_transcript
  ENST00000479540 HELZ2-005 63570126-63574239 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370082ENST00000427522ENST00000454223ENST00000467148ENST00000478861ENST00000479540
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370082 N/A N/A N/A 0.120±0.00 N/A N/A N/A 1.642±0.00 0.660±0.00 1.047±0.00 N/A N/A N/A N/A
ENST00000427522 N/A 2.014±0.00 N/A 0.408±0.29 1.080±0.41 1.106±0.00 N/A 1.986±0.00 1.633±0.00 3.771±0.00 0.201±0.05 3.540±3.03 1.409±0.48 0.676±0.38
ENST00000454223 N/A N/A N/A N/A N/A N/A N/A N/A 1.472±0.00 N/A N/A N/A N/A N/A
ENST00000467148 1.873±0.00 1.286±0.00 0.080±0.00 0.312±0.22 1.161±0.43 0.619±0.02 0.413±0.00 0.635±0.00 0.220±0.14 0.558±0.00 N/A 2.216±0.22 1.036±0.21 0.310±0.00
ENST00000478861 N/A N/A N/A 1.658±0.00 N/A 1.595±0.00 2.863±0.00 N/A 1.832±0.00 7.752±0.00 0.596±0.00 10.591±4.51 3.667±0.00 1.072±0.20
ENST00000479540 N/A N/A N/A N/A 0.895±0.00 N/A N/A N/A N/A N/A N/A 1.047±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012G CIL_00012G_0001 CGP 20:63547891-63574239
CIL_00012X CIL_00012X_0001 CGP 20:63558086-63627041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0016020 IDA membrane
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012600 HELZ2 (2 of 3) helicase with zinc finger 2, transcriptional coactivator protein_coding Danio_rerio
ENSDARG00000016527 helz2 helicase with zinc finger 2, transcriptional coactivator protein_coding Danio_rerio
ENSMUSG00000027580 Helz2 helicase with zinc finger 2, transcriptional coactivator protein_coding Mus_musculus

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