C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin T type 3 (skeletal, fast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130595 TNNT3 9606 + 11:1919562-1938706 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000278317 TNNT3-001 1919562-1938706 protein_coding
  ENST00000344578 TNNT3-011 1919725-1938492 protein_coding
  ENST00000381557 TNNT3-006 1919706-1938701 protein_coding
  ENST00000381558 TNNT3-004 1921359-1938706 protein_coding
  ENST00000381563 TNNT3-012 1919723-1938492 protein_coding
  ENST00000381579 TNNT3-003 1919706-1938706 protein_coding
  ENST00000381589 TNNT3-002 1919706-1938706 protein_coding
  ENST00000397301 TNNT3-010 1922867-1938492 protein_coding
  ENST00000397304 TNNT3-014 1922875-1938492 protein_coding
  ENST00000446240 TNNT3-015 1922875-1938492 protein_coding
  ENST00000453458 TNNT3-007 1919706-1934919 protein_coding
  ENST00000473100 TNNT3-016 1938200-1938702 processed_transcript
  ENST00000492075 TNNT3-009 1924918-1934655 processed_transcript
  ENST00000493234 TNNT3-008 1933873-1935581 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000278317ENST00000344578ENST00000381557ENST00000381558ENST00000381563ENST00000381579ENST00000381589ENST00000397301ENST00000397304ENST00000453458ENST00000473100ENST00000492075ENST00000493234
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000278317 N/A N/A N/A N/A N/A N/A 4.350±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000344578 N/A N/A N/A N/A 0.281±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000381557 N/A N/A N/A N/A 88.731±0.00 N/A 2.657±0.00 N/A N/A N/A N/A N/A N/A 7.675±0.00
ENST00000381558 N/A N/A N/A N/A N/A N/A 0.145±0.00 N/A N/A N/A N/A 0.046±0.00 N/A N/A
ENST00000381563 N/A N/A N/A 0.096±0.07 0.550±0.00 N/A N/A N/A N/A N/A 147.928±18.09 N/A N/A N/A
ENST00000381579 N/A N/A N/A N/A N/A N/A N/A N/A 0.867±0.00 N/A 118.379±27.09 N/A N/A N/A
ENST00000381589 23.294±0.00 N/A N/A N/A 117.932±117.49 5.050±0.00 6.855±0.00 N/A 1.947±0.00 0.777±0.00 325.099±69.67 N/A 1.854±0.00 5.867±3.06
ENST00000397301 N/A 1.428±0.00 N/A N/A N/A N/A 8.138±0.00 N/A 0.921±0.00 N/A N/A N/A N/A N/A
ENST00000397304 13.045±0.00 1.938±0.00 N/A 0.502±0.00 N/A 2.072±0.00 N/A N/A N/A 2.158±0.00 217.004±0.00 0.648±0.60 21.675±11.65 7.663±6.21
ENST00000453458 N/A N/A N/A N/A N/A 0.411±0.00 N/A 0.457±0.00 0.031±0.00 N/A N/A N/A N/A N/A
ENST00000473100 N/A 2.832±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.925±0.00 N/A N/A
ENST00000492075 N/A N/A N/A N/A N/A N/A N/A 0.275±0.00 N/A N/A N/A N/A N/A N/A
ENST00000493234 N/A 0.895±0.00 0.039±0.00 N/A N/A N/A N/A 0.257±0.00 0.968±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0001 VISTA 11:1663842-2266142
CIL_0007RG CIL_0007RG_0001 VISTA 11:1668349-2271510
CIL_00097V CIL_00097V_0001 VISTA 11:1688064-2293510
CIL_0003FO CIL_0003FO_0002 CGP 11:1889145-1938706
CIL_00048I CIL_00048I_0001 CGP 11:1919562-1984522

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003009 IDA skeletal muscle contraction
GO:0003779 IDA actin binding
GO:0005523 IMP tropomyosin binding
GO:0005829 TAS cytosol
GO:0005861 IDA:IEA troponin complex
GO:0006200 IDA ATP catabolic process
GO:0006937 IEA regulation of muscle contraction
GO:0006942 IDA regulation of striated muscle contraction
GO:0030049 TAS muscle filament sliding
GO:0030172 IPI troponin C binding
GO:0030899 IDA calcium-dependent ATPase activity
GO:0031013 IPI troponin I binding
GO:0043462 IDA regulation of ATPase activity
GO:0048306 IDA calcium-dependent protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030270 tnnt3a troponin T3a, skeletal, fast protein_coding Danio_rerio
ENSDARG00000068457 tnnt3b troponin T3b, skeletal, fast protein_coding Danio_rerio
ENSMUSG00000061723 Tnnt3 troponin T3, skeletal, fast protein_coding Mus_musculus

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