C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exosome component 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130713 EXOSC2 9606 + 9:130693721-130704894 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372350 EXOSC2-005 130693787-130702293 protein_coding
  ENST00000372351 EXOSC2-002 130693786-130704861 protein_coding
  ENST00000372352 EXOSC2-006 130693780-130704861 protein_coding
  ENST00000372358 EXOSC2-001 130693721-130704861 protein_coding
  ENST00000430138 EXOSC2-007 130693775-130704861 processed_transcript
  ENST00000463488 EXOSC2-010 130693806-130699681 processed_transcript
  ENST00000467138 EXOSC2-008 130700842-130704861 processed_transcript
  ENST00000490641 EXOSC2-009 130693780-130699791 processed_transcript
  ENST00000491115 EXOSC2-004 130693721-130703774 processed_transcript
  ENST00000495699 EXOSC2-003 130693806-130703181 protein_coding
  ENST00000546165 EXOSC2-201 130693760-130704894 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372350ENST00000372351ENST00000372352ENST00000372358ENST00000430138ENST00000467138ENST00000495699ENST00000546165
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372350 N/A N/A N/A N/A N/A N/A 0.565±0.00 N/A N/A N/A 1.910±0.00 N/A N/A N/A
ENST00000372351 N/A 2.707±0.00 0.500±0.00 N/A N/A 0.428±0.00 N/A N/A N/A N/A 0.236±0.00 N/A N/A N/A
ENST00000372352 N/A N/A N/A N/A N/A 1.889±0.00 N/A N/A N/A 0.614±0.00 N/A N/A N/A N/A
ENST00000372358 2.563±0.00 N/A 0.560±0.00 3.560±0.25 1.731±0.40 1.866±0.00 0.806±0.35 2.250±0.00 3.288±0.87 1.636±0.33 4.130±0.00 4.975±1.85 5.997±1.24 2.370±0.94
ENST00000430138 0.626±0.00 4.038±0.00 N/A 1.409±0.00 0.947±0.01 0.603±0.00 N/A N/A N/A N/A 0.727±0.00 2.215±0.35 N/A 1.591±0.00
ENST00000467138 N/A 2.120±0.00 0.578±0.00 N/A 0.688±0.00 0.631±0.03 0.521±0.00 N/A 0.425±0.00 0.651±0.07 N/A 1.999±0.14 N/A 0.793±0.00
ENST00000495699 3.089±0.00 N/A N/A N/A 3.979±0.00 N/A 0.898±0.47 3.215±0.00 2.137±0.00 2.603±0.00 6.045±0.00 5.013±0.00 6.503±0.00 N/A
ENST00000546165 N/A N/A N/A N/A 0.858±0.00 N/A N/A N/A N/A 0.726±0.20 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000936 CIL_000936_0001 VISTA 9:130178260-130779710
CIL_0008XQ CIL_0008XQ_0001 VISTA 9:130365168-130965841
CIL_0006IB CIL_0006IB_0001 CGP 9:130664594-130704894
CIL_0007CW CIL_0007CW_0002 CGP 9:130693721-130887675

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 TAS 3'-5'-exoribonuclease activity
GO:0000178 IEA exosome (RNase complex)
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006364 IEA rRNA processing
GO:0008312 TAS 7S RNA binding
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030307 IMP positive regulation of cell growth
GO:0043928 TAS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0090503 TAS RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028688 exosc2 exosome component 2 protein_coding Danio_rerio
ENSMUSG00000039356 Exosc2 exosome component 2 protein_coding Mus_musculus

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