C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitination factor E4B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130939 UBE4B 9606 + 1:10032832-10181239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253251 UBE4B-002 10032832-10180367 protein_coding
  ENST00000343090 UBE4B-001 10033596-10181239 protein_coding
  ENST00000377153 UBE4B-005 10033274-10073118 protein_coding
  ENST00000462658 UBE4B-008 10100861-10103185 retained_intron
  ENST00000465408 UBE4B-010 10179016-10179950 processed_transcript
  ENST00000466379 UBE4B-003 10128339-10145599 retained_intron
  ENST00000470736 UBE4B-011 10122042-10145039 protein_coding
  ENST00000475795 UBE4B-007 10107331-10132480 processed_transcript
  ENST00000487244 UBE4B-004 10170956-10180016 retained_intron
  ENST00000488228 UBE4B-009 10158354-10171189 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253251ENST00000343090ENST00000470736
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253251 3.569±0.00 2.560±0.00 N/A 3.644±2.13 2.926±0.00 2.316±1.55 3.467±0.00 1.761±0.45 1.323±0.00 6.791±0.00 6.103±3.15 4.410±3.30 4.285±1.04
ENST00000343090 N/A 0.943±0.00 1.198±0.00 1.273±0.51 2.370±0.00 4.769±2.83 0.797±0.20 N/A 1.449±0.00 6.698±4.83 5.751±0.88 2.564±0.00 1.041±0.00
ENST00000470736 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.147±0.00 15.632±0.00 8.445±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 TAS:IEA ubiquitin ligase complex
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008626 IDA granzyme-mediated apoptotic signaling pathway
GO:0009411 IDA response to UV
GO:0016567 IEA protein ubiquitination
GO:0019899 ISS enzyme binding
GO:0034450 IEA ubiquitin-ubiquitin ligase activity
GO:0042787 TAS protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037017 ube4b ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000028960 Ube4b ubiquitination factor E4B protein_coding Mus_musculus

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