C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Nedd4 family interacting protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131507 NDFIP1 9606 + 5:142108505-142154443 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253814 NDFIP1-001 142108505-142154443 protein_coding
  ENST00000503388 NDFIP1-002 142142978-142154195 retained_intron
  ENST00000505614 NDFIP1-004 142135730-142138192 retained_intron
  ENST00000509436 NDFIP1-003 142108788-142134068 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253814ENST00000503388
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253814 21.814±0.00 14.333±0.00 6.804±0.00 73.206±8.94 17.303±7.20 13.588±4.68 12.190±4.76 30.045±7.98 18.653±3.40 18.774±3.68 7.090±3.41 20.097±8.33 25.905±1.35 24.992±4.42
ENST00000503388 N/A N/A 0.818±0.00 N/A 1.319±0.00 N/A N/A N/A N/A N/A 0.597±0.00 1.338±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00062Z CIL_00062Z_0002 CGP 5:141991749-142154443
CIL_0006Q6 CIL_0006Q6_0001 CGP 5:142108505-142326455

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002761 IEA regulation of myeloid leukocyte differentiation
GO:0002829 IEA negative regulation of type 2 immune response
GO:0004871 IMP signal transducer activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005768 IEA endosome
GO:0005794 IEA Golgi apparatus
GO:0005938 IEA cell cortex
GO:0006879 IMP cellular iron ion homeostasis
GO:0007165 IMP signal transduction
GO:0010629 IMP negative regulation of gene expression
GO:0016021 IEA integral component of membrane
GO:0031398 IMP positive regulation of protein ubiquitination
GO:0032410 IMP negative regulation of transporter activity
GO:0032713 IEA negative regulation of interleukin-4 production
GO:0042130 IEA negative regulation of T cell proliferation
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043162 IEA ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045619 IEA regulation of lymphocyte differentiation
GO:0045732 IEA positive regulation of protein catabolic process
GO:0048294 IEA negative regulation of isotype switching to IgE isotypes
GO:0048302 IEA regulation of isotype switching to IgG isotypes
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050699 IEA WW domain binding
GO:0050728 IEA negative regulation of inflammatory response
GO:0051224 IMP negative regulation of protein transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008057 ndfip1l Nedd4 family interacting protein 1, like protein_coding Danio_rerio
ENSDARG00000013979 ndfip1 Nedd4 family interacting protein 1 protein_coding Danio_rerio
ENSMUSG00000024425 Ndfip1 Nedd4 family interacting protein 1 protein_coding Mus_musculus

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