C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Nedd4 family interacting protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024425 Ndfip1 10090 + 18:38418975-38464399 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025293 Ndfip1-201 38418975-38464399 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025293
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025293 82.465±5.36 646.331±106.66 38.723±8.58 110.691±5.38 81.019±39.26 74.224±35.21 26.649±2.73 76.284±24.64 71.287±53.46 43.051±18.85 13.934±3.00 201.722±108.29 43.874±11.58 50.800±18.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00062Z CIL_00062Z_0003 CGP 18:38327558-38464399
CIL_0006Q6 CIL_0006Q6_0002 CGP 18:38418975-38601268

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002761 IMP regulation of myeloid leukocyte differentiation
GO:0002829 IMP negative regulation of type 2 immune response
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005768 IEA endosome
GO:0005794 IDA Golgi apparatus
GO:0005938 IDA cell cortex
GO:0006879 IEA cellular iron ion homeostasis
GO:0007165 IEA signal transduction
GO:0010629 IEA negative regulation of gene expression
GO:0016021 ISM integral component of membrane
GO:0030173 IC integral component of Golgi membrane
GO:0031398 IEA positive regulation of protein ubiquitination
GO:0032410 IEA negative regulation of transporter activity
GO:0032713 IMP negative regulation of interleukin-4 production
GO:0042130 IMP negative regulation of T cell proliferation
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043162 IGI ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045619 IMP regulation of lymphocyte differentiation
GO:0045732 IDA positive regulation of protein catabolic process
GO:0048294 IMP negative regulation of isotype switching to IgE isotypes
GO:0048302 IMP regulation of isotype switching to IgG isotypes
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050699 IPI WW domain binding
GO:0050728 IMP negative regulation of inflammatory response
GO:0051224 IEA negative regulation of protein transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008057 ndfip1l Nedd4 family interacting protein 1, like protein_coding Danio_rerio
ENSDARG00000013979 ndfip1 Nedd4 family interacting protein 1 protein_coding Danio_rerio
ENSG00000131507 NDFIP1 Nedd4 family interacting protein 1 protein_coding Homo_sapiens

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