C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter), member 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132164 SLC6A11 9606 + 3:10816200-10940733 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254488 SLC6A11-001 10816200-10940733 protein_coding
  ENST00000454147 SLC6A11-002 10816201-10825498 protein_coding
  ENST00000464828 SLC6A11-003 10933966-10935397 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254488ENST00000454147
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254488 0.008±0.00 0.021±0.00 0.034±0.00 7.725±4.63 0.052±0.00 0.014±0.00 N/A 0.013±0.00 N/A N/A N/A 0.109±0.05 0.273±0.18 1.178±0.62
ENST00000454147 0.004±0.00 0.043±0.00 N/A 2.260±0.00 0.066±0.00 0.015±0.00 0.020±0.00 0.021±0.00 0.048±0.03 0.049±0.00 0.049±0.00 0.043±0.03 0.099±0.06 0.316±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001NW CIL_0001NW_0001 CGP 3:10324023-10940733
CIL_0001LQ CIL_0001LQ_0001 CGP 3:10816200-11039247

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004014 IEA adenosylmethionine decarboxylase activity
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005332 IEA gamma-aminobutyric acid:sodium symporter activity
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006836 IEA neurotransmitter transport
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0007420 IEA brain development
GO:0008295 IEA spermidine biosynthetic process
GO:0015812 IEA gamma-aminobutyric acid transport
GO:0016020 IEA membrane
GO:0016021 TAS:IEA integral component of membrane
GO:0042165 IEA neurotransmitter binding
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040435 SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 protein_coding Danio_rerio
ENSMUSG00000030307 Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 protein_coding Mus_musculus

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