C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAN, member RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132341 RAN 9606 + 12:130871879-130877678 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000392367 RAN-005 130872096-130875963 protein_coding
  ENST00000392369 RAN-003 130872070-130876281 protein_coding
  ENST00000448750 RAN-004 130872037-130877676 protein_coding
  ENST00000464211 RAN-011 130872096-130875924 retained_intron
  ENST00000477395 RAN-002 130872070-130875665 retained_intron
  ENST00000535090 RAN-010 130872076-130875784 protein_coding
  ENST00000536606 RAN-009 130872047-130875709 nonsense_mediated_decay
  ENST00000537745 RAN-007 130872066-130873839 retained_intron
  ENST00000539498 RAN-006 130873103-130875639 retained_intron
  ENST00000541630 RAN-008 130872066-130876733 protein_coding
  ENST00000541679 RAN-012 130872082-130876234 protein_coding
  ENST00000543796 RAN-001 130871879-130877678 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392367ENST00000392369ENST00000535090ENST00000541679ENST00000543796
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392367 N/A N/A 2.156±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000392369 21.458±0.00 51.553±0.00 N/A 48.446±0.00 22.819±0.00 38.097±0.00 21.355±0.00 54.525±0.00 26.301±0.00 44.494±0.00 28.039±0.00 104.633±67.58 98.636±24.35 141.093±20.94
ENST00000535090 20.132±0.00 N/A 3.152±0.00 N/A N/A 17.000±9.52 2.719±0.00 5.843±0.00 N/A 6.478±0.00 7.269±0.00 23.829±0.00 N/A N/A
ENST00000541679 29.932±0.00 58.627±0.00 6.732±0.00 N/A 31.991±0.00 22.870±10.32 24.855±0.00 35.398±0.00 28.977±0.00 55.755±0.00 19.490±6.23 125.672±0.00 79.868±7.25 100.799±0.00
ENST00000543796 16.382±0.00 19.254±0.00 3.188±0.00 34.503±2.23 15.270±0.88 12.253±3.12 7.318±1.18 11.009±2.56 9.847±3.22 10.617±0.64 8.594±2.70 25.474±3.36 15.696±5.97 27.557±2.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000430 CIL_000430_0001 CGP 12:130789600-130877678
CIL_00042Z CIL_00042Z_0001 CGP 12:130871879-131141469

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000055 IMP ribosomal large subunit export from nucleus
GO:0000056 IMP ribosomal small subunit export from nucleus
GO:0000785 IDA chromatin
GO:0003682 TAS chromatin binding
GO:0003713 NAS transcription coactivator activity
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005643 NAS nuclear pore
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006259 TAS DNA metabolic process
GO:0006606 IEA protein import into nucleus
GO:0006611 IDA protein export from nucleus
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0007052 TAS mitotic spindle organization
GO:0007067 TAS mitotic nuclear division
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007286 IEA spermatid development
GO:0010467 TAS gene expression
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016032 TAS viral process
GO:0019003 IEA GDP binding
GO:0019058 TAS viral life cycle
GO:0019904 IEA protein domain specific binding
GO:0030036 IEA actin cytoskeleton organization
GO:0030521 NAS androgen receptor signaling pathway
GO:0032092 IDA positive regulation of protein binding
GO:0034613 IEA cellular protein localization
GO:0034629 IEA cellular protein complex localization
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0050681 NAS androgen receptor binding
GO:0070062 IDA extracellular vesicular exosome
GO:0075733 TAS intracellular transport of virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057026 ran ras-related nuclear protein protein_coding Danio_rerio
ENSMUSG00000029430 Ran RAN, member RAS oncogene family protein_coding Mus_musculus

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