C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132570 PCBD2 9606 + 5:134904906-135007959 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254908 PCBD2-001 134904906-134961277 protein_coding
  ENST00000504352 PCBD2-005 134905173-135007959 nonsense_mediated_decay
  ENST00000510013 PCBD2-004 134908830-134959095 processed_transcript
  ENST00000512783 PCBD2-002 134905120-134969660 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254908ENST00000510013ENST00000512783
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254908 1.098±0.00 1.927±0.00 N/A 0.909±0.39 1.611±0.85 0.944±0.00 5.153±0.00 2.281±1.28 1.652±0.07 1.008±0.00 4.709±0.97 1.754±0.09 1.454±0.13 N/A
ENST00000510013 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.659±0.00 N/A N/A
ENST00000512783 0.439±0.00 0.767±0.00 0.683±0.00 0.425±0.00 0.743±0.50 0.333±0.00 0.522±0.30 0.708±0.59 0.570±0.06 0.460±0.31 1.008±0.70 0.579±0.16 0.205±0.09 0.817±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JT CIL_0007JT_0002 UCNEbase 5:134524545-135264654
CIL_0009AP CIL_0009AP_0001 VISTA 5:134719818-135321709
CIL_0005XS CIL_0005XS_0001 CGP 5:134873803-135007959
CIL_0005XV CIL_0005XV_0001 CGP 5:134904906-135011707

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004505 IEA phenylalanine 4-monooxygenase activity
GO:0005515 IPI protein binding
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0006729 IEA tetrahydrobiopterin biosynthetic process
GO:0008124 IEA 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0051289 IEA protein homotetramerization
GO:0051291 IEA protein heterooligomerization
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021496 Pcbd2 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 protein_coding Mus_musculus

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